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The cardiovascular system: mathematical modelling, numerical algorithms and clinical applications
Mathematical and numerical modelling of the cardiovascular system is a research topic that
has attracted remarkable interest from the mathematical community because of its intrinsic …
has attracted remarkable interest from the mathematical community because of its intrinsic …
lifex-cfd: An open-source computational fluid dynamics solver for cardiovascular applications
Computational fluid dynamics (CFD) is an important tool for the simulation of the
cardiovascular function and dysfunction. Due to the complexity of the anatomy, the …
cardiovascular function and dysfunction. Due to the complexity of the anatomy, the …
Review of numerical methods for simulation of mechanical heart valves and the potential for blood clotting
Even though the mechanical heart valve (MHV) has been used routinely in clinical practice
for over 60 years, the occurrence of serious complications such as blood clotting remains to …
for over 60 years, the occurrence of serious complications such as blood clotting remains to …
Comparison of hemodynamic and structural indices of ascending thoracic aortic aneurysm as predicted by 2-way FSI, CFD rigid wall simulation and patient-specific …
Patient-specific computational modeling is increasingly being used to predict structural and
hemodynamic parameters, especially when current clinical tools are not accessible. Indeed …
hemodynamic parameters, especially when current clinical tools are not accessible. Indeed …
Characterization of abnormal wall shear stress using 4D flow MRI in human bicuspid aortopathy
There exists considerable controversy surrounding the timing and extent of aortic resection
for patients with BAV disease. Since abnormal wall shear stress (WSS) is potentially …
for patients with BAV disease. Since abnormal wall shear stress (WSS) is potentially …
Computational comparison of regional stress and deformation characteristics in tricuspid and bicuspid aortic valve leaflets
The bicuspid aortic valve (BAV) is the most common congenital valvular defect and a major
risk factor for secondary calcific aortic valve disease. While hemodynamics is presumed to …
risk factor for secondary calcific aortic valve disease. While hemodynamics is presumed to …
A patient-specific aortic valve model based on moving resistive immersed implicit surfaces
In this paper, we propose a full computational framework to simulate the hemodynamics in
the aorta including the valve. Closed and open valve surfaces, as well as the lumen aorta …
the aorta including the valve. Closed and open valve surfaces, as well as the lumen aorta …
Simulations of morphotype-dependent hemodynamics in non-dilated bicuspid aortic valve aortas
Bicuspid aortic valves (BAVs) generate flow abnormalities that may promote aortopathy.
While positive helix fraction (PHF) index, flow angle (θ), flow displacement (d) and wall …
While positive helix fraction (PHF) index, flow angle (θ), flow displacement (d) and wall …
Volumetric quantification of absolute local normalized helicity in patients with bicuspid aortic valve and aortic dilatation
Purpose Absolute local normalized helicity (LNH) can differentiate flow alterations in the
aorta between healthy controls and bicuspid aortic valve (BAV) patients. Methods A total of …
aorta between healthy controls and bicuspid aortic valve (BAV) patients. Methods A total of …
Hemodynamic assessment in bicuspid aortic valve disease and aortic dilation: new insights from voxel-by-voxel analysis of reverse flow, stasis, and energetics
Objectives: Clinical management decisions surrounding ascending aorta (AAo) dilation in
bicuspid aortic valve (BAV) disease benefit from personalized predictive tools. 4D-flow MRI …
bicuspid aortic valve (BAV) disease benefit from personalized predictive tools. 4D-flow MRI …