Polarisation optics for biomedical and clinical applications: a review

C He, H He, J Chang, B Chen, H Ma… - Light: Science & …, 2021 - nature.com
Many polarisation techniques have been harnessed for decades in biological and clinical
research, each based upon measurement of the vectorial properties of light or the vectorial …

Illuminating cellular architecture and dynamics with fluorescence polarization microscopy

WF Dean, AL Mattheyses - Journal of Cell Science, 2024 - journals.biologists.com
ABSTRACT Ever since Robert Hooke's 17th century discovery of the cell using a humble
compound microscope, light–matter interactions have continuously redefined our …

Polarization-sensitive intensity diffraction tomography

S Song, J Kim, T Moon, B Seong, W Kim… - Light: Science & …, 2023 - nature.com
Optical anisotropy, which is an intrinsic property of many materials, originates from the
structural arrangement of molecular structures, and to date, various polarization-sensitive …

Global fitting for high-accuracy multi-channel single-molecule localization

Y Li, W Shi, S Liu, I Cavka, YL Wu, U Matti… - Nature …, 2022 - nature.com
Multi-channel detection in single-molecule localization microscopy greatly increases
information content for various biological applications. Here, we present globLoc, a graphics …

Three-dimensional dipole orientation map** with high temporal-spatial resolution using polarization modulation

S Zhong, L Qiao, X Ge, X Xu, Y Fu, S Gao, K Zhanghao… - PhotoniX, 2024 - Springer
Fluorescence polarization microscopy is widely used in biology for molecular orientation
properties. However, due to the limited temporal resolution of single-molecule orientation …

Vectorial adaptive optics

C He, J Antonello, MJ Booth - ELight, 2023 - Springer
Adaptive optics normally concerns the feedback correction of phase aberrations. Such
correction has been of benefit in various optical systems, with applications ranging in scale …

Characterizing dark state kinetics and single molecule fluorescence of FusionRed and FusionRed-MQ at low irradiances

S Mukherjee, C Thomas, R Wilson… - Physical Chemistry …, 2022 - pubs.rsc.org
The presence of dark states causes fluorescence intermittency of single molecules due to
transitions between “on” and “off” states. Genetically encodable markers such as fluorescent …

Simultaneous super-resolution estimation of single-molecule position and orientation with minimal photon fluxes

Z Zhan, C Li, X Liu, X Sun, C He, C Kuang, X Liu - Optics Express, 2022 - opg.optica.org
The orientation of a single molecule provides valuable information on fundamental
biological processes. We report a technique for the simultaneous estimation of single …

OOPS: Object-Oriented Polarization Software for analysis of fluorescence polarization microscopy images

WF Dean, TJ Nawara, RM Albert… - PLOS Computational …, 2024 - journals.plos.org
Most essential cellular functions are performed by proteins assembled into larger
complexes. Fluorescence Polarization Microscopy (FPM) is a powerful technique that goes …

Combining single-molecule super-resolved localization microscopy with fluorescence polarization imaging to study cellular processes

JW Shepherd, AL Payne-Dwyer, JE Lee… - Journal of Physics …, 2021 - iopscience.iop.org
Super-resolution microscopy has catalyzed valuable insights into the sub-cellular,
mechanistic details of many different biological processes across a wide range of cell types …