Corneal opacity is the 5th leading cause of blindness and visual impairment globally,
affecting~ 6 million of the world population. In addition, it is responsible for 1.5–2.0 million …

The cornea is a specialized, transparent, avascular, immune-privileged, and heavily
innervated tissue that affords 2/3rd of refraction to the eye. Ocular injuries, infections, and …

High-risk (HR) corneal transplantation presents a formidable challenge, with over 50% of
grafts experiencing rejection despite intensive postoperative care involving frequent topical …

To review challenges in the diagnosis and management of Acanthamoeba keratitis (AK),
along with prognostic factors, in order to help ophthalmologists avoid misdiagnosis …

Regulatory T cells (Tregs) are crucial mediators of immune homeostasis. They regulate
immune response by suppressing inflammation and promoting self-tolerance. In addition to …

Exosomes, nanosized extracellular vesicles of 30–150 nm, are shed by almost all cell types.
Bearing proteins, lipids, RNAs, and DNAs, exosomes have emerged as vital biological …

Graft-versus-host disease is a common complication following allogeneic hematopoetic
stem cell transplantation that can affect multiple organ systems, including the eyes. Ocular …

The search for alternatives to allotransplants is driven by the shortage of corneal donors and
is demanding because of the limitations of the alternatives. Indeed, current progress in …

Purpose Graft-versus-host disease (GVHD) is a major complication of allogeneic
hematopoietic stem cells transplantation, occurring in about half of transplanted patients …

Macrophages are critical mediators of tissue vascularization both in health and disease. In
multiple tissues, macrophages have been identified as important regulators of both blood …