Perioperative stroke in noncardiac, nonneurosurgical surgery.

JL Ng, MT Chan, AW Gelb - Anesthesiology, 2011 - europepmc.org
Perioperative stroke after noncardiac, nonneurosurgical procedures is more common than
generally acknowledged. It is reported to have an incidence of 0.05-7% of patients. Most are …

Safety of short-term discontinuation of antiplatelet therapy in patients with drug-eluting stents

MJ Eisenberg, PR Richard, D Libersan, KB Filion - Circulation, 2009 - Am Heart Assoc
Background—Antiplatelet therapy is often discontinued in patients with drug-eluting stents
who are undergoing surgical procedures. However, discontinuation of antiplatelet therapy is …

Stent thrombogenicity early in high-risk interventional settings is driven by stent design and deployment and protected by polymer-drug coatings

K Kolandaivelu, R Swaminathan, WJ Gibson… - Circulation, 2011 - Am Heart Assoc
Background—Stent thrombosis is a lethal complication of endovascular intervention.
Concern has been raised about the inherent risk associated with specific stent designs and …

Late clinical events after clopidogrel discontinuation may limit the benefit of drug-eluting stents: an observational study of drug-eluting versus bare-metal stents

M Pfisterer, HP Brunner-La Rocca, PT Buser… - Journal of the american …, 2006 - jacc.org
Objectives: We sought to define the incidence of late clinical events and late stent
thrombosis in patients treated with drug-eluting (DES) versus bare-metal stents (BMS) after …

Incidence of death and acute myocardial infarction associated with stop** clopidogrel after acute coronary syndrome

PM Ho, ED Peterson, L Wang, DJ Magid, SD Fihn… - Jama, 2008 - jamanetwork.com
Context It is unknown whether patients are at increased short-term risk for adverse events
following clopidogrel cessation. Objective To assess the rates of adverse events after …

Impact of platelet reactivity on cardiovascular outcomes in patients with type 2 diabetes mellitus and coronary artery disease

DJ Angiolillo, E Bernardo, M Sabaté… - Journal of the American …, 2007 - jacc.org
Objectives: This study sought to determine the prognostic implications of high platelet
reactivity (HPR) assessed in type 2 diabetes mellitus (T2DM) patients while in their steady …

Insulin therapy is associated with platelet dysfunction in patients with type 2 diabetes mellitus on dual oral antiplatelet treatment

DJ Angiolillo, E Bernardo, C Ramírez, MA Costa… - Journal of the American …, 2006 - jacc.org
Objectives: This study sought to assess the influence of type 2 diabetes mellitus (T2DM) and
the impact of hypoglycemic treatment (insulin vs. noninsulin) on platelet function profiles in …

Precision medicine in interventional cardiology: implications for antiplatelet therapy in patients undergoing percutaneous coronary intervention

M Galli, L Ortega-Paz, F Franchi, F Rollini… - …, 2022 - Taylor & Francis
Precision medicine is a medical model that proposes the customization of medical
treatments to the individual patient, as opposed to a one-drug-fits-all model. Such a …

Platelets as therapeutic targets to prevent atherosclerosis

H Nording, L Baron, HF Langer - Atherosclerosis, 2020 - Elsevier
Cardiovascular disease remains the main cause of death worldwide. For this reason,
strategies for the primary prevention of atherosclerosis and atherosclerosis-related …

Effects of P2Y12 receptor antagonists beyond platelet inhibition – comparison of ticagrelor with thienopyridines

S Nylander, R Schulz - British journal of pharmacology, 2016 - Wiley Online Library
The effect and clinical benefit of P2Y12 receptor antagonists may not be limited to platelet
inhibition and the prevention of arterial thrombus formation. Potential additional effects …