Background Fusobacterium nucleatum (F. nucleatum) is an anaerobic oral commensal and
the major coaggregation bridge organism linking early and late colonisers. In recent years, a …

The evidence of a connection between the peripheral inflammatory processes and
neurodegenerative diseases of the central nervous system is becoming more apparent. This …

The relationship between periodontitis and systemic diseases, notably including
atherosclerosis and diabetes, has been studied for several years. Porphyromonas …

Alzheimer's disease (AD) is the most serious age-related neurodegenerative disease and
causes destructive and irreversible cognitive decline. Failures in the development of …

Background The emergence of the novel, pathogenic severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) has caused a global health emergency. SARS-CoV-2 is highly …

The integrity of the blood–brain barrier (BBB) is essential for normal central nervous system
(CNS) functioning. Considering the significance of BBB in maintaining homeostasis and the …

The blood–brain barrier, which is formed by tightly interconnected microvascular endothelial
cells, separates the brain from the peripheral circulation. Together with other central nervous …

The gut microbiota is symbiotic with the human host and has been extensively studied in
recent years resulting in increasing awareness of the effects of the gut microbiota on human …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which causes the
coronavirus disease (COVID-19), is currently infecting millions of people worldwide and is …

As the population ages, the incidence of age-related neurodegenerative diseases is rapidly
increasing, and novel approaches to mitigate this soaring prevalence are sorely needed …