Endometrial Angiogenesis of Abnormal Uterine Bleeding and Infertility in Patients with Uterine Fibroids—A Systematic Review

EE Don, MA Middelkoop, WJK Hehenkamp… - International journal of …, 2023 - mdpi.com
Uterine fibroids are the most common benign tumors in women, with abnormal uterine
bleeding (AUB) as the main reported symptom. Additionally, an association between fibroids …

Adrenomedullin reduces endothelial hyperpermeability

S Hippenstiel, M Witzenrath, B Schmeck… - Circulation …, 2002 - Am Heart Assoc
Endothelial hyperpermeability induced by inflammatory mediators is a hallmark of sepsis
and adult respiratory distress syndrome. Increased levels of the regulatory peptide …

Adrenomedullin and tumour angiogenesis

LL Nikitenko, SB Fox, S Kehoe, MCP Rees… - British journal of …, 2006 - nature.com
The angiogenic activity of peptide adrenomedullin (AM) was first shown in 1998. Since then,
a number of reports have confirmed the ability of AM to induce the growth and migration of …

Adrenomedullin and endothelial barrier function

B Temmesfeld-Wollbrueck, AC Hocke… - Thrombosis and …, 2007 - thieme-connect.com
Although loss of endothelial barrier function is a hallmark of every acute inflammation and
contributes to fatal loss of organ function during severe infections, there is no sufficient …

CL/RAMP2 and CL/RAMP3 produce pharmacologically distinct adrenomedullin receptors: a comparison of effects of adrenomedullin22–52, CGRP8–37 and …

DL Hay, SG Howitt, AC Conner… - British journal of …, 2003 - Wiley Online Library
Adrenomedullin (AM) has two known receptors formed by the calcitonin receptor‐like
receptor (CL) and receptor activity‐modifying protein (RAMP) 2 or 3: We report the effects of …

Adrenomedullin promotes formation of xenografted endometrial tumors by stimulation of autocrine growth and angiogenesis

MK Oehler, S Hague, MCP Rees, R Bicknell - Oncogene, 2002 - nature.com
The angiogenic peptide adrenomedullin (ADM) has been implicated as a mediator of the
increased risk of endometrial hyperplasia and cancer resulting from the use of tamoxifen for …

Transcriptional regulation of the CRLR gene in human microvascular endothelial cells by hypoxia

LL Nikitenko, DM Smith, R Bicknell… - The FASEB …, 2003 - Wiley Online Library
Adrenomedullin is a 52 amino acid peptide that shows a remarkable range of effects on the
vasculature that include inter alia, vasodilatation, regulation of permeability, inhibition of …

Adrenomedullin reduces Staphylococcus aureus α-toxin–induced rat ileum microcirculatory damage

B Brell, B Temmesfeld-Wollbrück, I Altzschner… - Critical care …, 2005 - journals.lww.com
Objective: Increased microvascular permeability and perfusion mismatch are hallmarks of
sepsis or septic shock. The intestinal mucosa is very sensitive to tissue hypoxia. Intestinal …

Tissue and plasma expression of the angiogenic peptide adrenomedullin in breast cancer

MK Oehler, DC Fischer, M Orlowska-Volk… - British journal of …, 2003 - nature.com
Adrenomedullin (ADM) is an angiogenic factor that has also been shown to be a mitogen
and a hypoxia survival factor for tumour cells. These properties point to ADM as a potential …

Regulation of pancreatic physiology by adrenomedullin and its binding protein

E Zudaire, F Cuttitta, A Martınez - Regulatory peptides, 2003 - Elsevier
Adrenomedullin (AM) is a 52 amino acid, multifunctional hormone. It is expressed in many
tissues of the human body including the pancreas, where it is mainly localized to the …