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[HTML][HTML] The potential use of simvastatin for cancer treatment: A review
JA Duarte, ALB de Barros, EA Leite - Biomedicine & Pharmacotherapy, 2021 - Elsevier
Statins, typically used to reduce lipid levels, have been rediscovered for exhibiting
anticancer activities. Among them, especially simvastatin may influence the proliferation …
anticancer activities. Among them, especially simvastatin may influence the proliferation …
Recent advances and prospects in gemcitabine drug delivery systems
Cancer is a community health hazard which progress at a fatal rate in various countries
across the globe. An agent used for chemotherapy should exhibit ideal properties to be an …
across the globe. An agent used for chemotherapy should exhibit ideal properties to be an …
Chitosan surface-modified PLGA nanoparticles loaded with cranberry powder extract as a potential oral delivery platform for targeting colon cancer cells
Nutraceutical cranberry powder extract (CBPE) has distinct polyphenols inhibiting colon
cancer growth and proliferation. However, its oral therapeutic efficacy is hindered because …
cancer growth and proliferation. However, its oral therapeutic efficacy is hindered because …
Nanoscale drug delivery systems for cancer therapy using paclitaxel—A review of challenges and latest progressions
Paclitaxel (PTX) is an effective anticancer chemical with a broad spectrum that was primarily
obtained from a curative shrub, specifically the bark of Taxus brevifolia tree. It belongs to a …
obtained from a curative shrub, specifically the bark of Taxus brevifolia tree. It belongs to a …
Acquired and intrinsic gemcitabine resistance in pancreatic cancer therapy: environmental factors, molecular profile and drug/nanotherapeutic approaches
A high number of cancer patients around the world rely on gemcitabine (GEM) for
chemotherapy. During local metastasis of cancers, surgery is beneficial for therapy, but …
chemotherapy. During local metastasis of cancers, surgery is beneficial for therapy, but …
[HTML][HTML] Boosting the anticancer activity of sunitinib malate in breast cancer through lipid polymer hybrid nanoparticles approach
In the current study, lipid-polymer hybrid nanoparticles (LPHNPs) fabricated with lipoid-90H
and chitosan, sunitinib malate (SM), an anticancer drug was loaded using lecithin as a …
and chitosan, sunitinib malate (SM), an anticancer drug was loaded using lecithin as a …
[HTML][HTML] Advances in pancreatic cancer treatment by Nano-based drug delivery systems
Pancreatic cancer represents one of the most lethal cancer types worldwide, with a 5-year
survival rate of less than 5%. Due to the inability to diagnose it promptly and the lack of …
survival rate of less than 5%. Due to the inability to diagnose it promptly and the lack of …
[HTML][HTML] Development of sustained release baricitinib loaded lipid-polymer hybrid nanoparticles with improved oral bioavailability
Baricitinib (BTB) is an orally administered Janus kinase inhibitor, therapeutically used for the
treatment of rheumatoid arthritis. Recently it has also been approved for the treatment of …
treatment of rheumatoid arthritis. Recently it has also been approved for the treatment of …
Nose to brain delivery of selegiline loaded PLGA/lipid nanoparticles: Synthesis, characterisation and brain pharmacokinetics evaluation
Parkinson's disease (PD) is the second most common progressive neurodegenerative
disease that promotes neuronal cell death. The primary treatment strategy for Parkinson's …
disease that promotes neuronal cell death. The primary treatment strategy for Parkinson's …
Sonication tailored enhance cytotoxicity of naringenin nanoparticle in pancreatic cancer: design, optimization, and in vitro studies
Objective: In vitro, optimization, characterization, and cytotoxic studies of NAR nanoparticles
(NPs) to against pancreatic cancer. Method: The sonication tailored Naringenin (NARG) …
(NPs) to against pancreatic cancer. Method: The sonication tailored Naringenin (NARG) …