The Huisgen reaction: milestones of the 1, 3‐dipolar cycloaddition

M Breugst, HU Reissig - Angewandte Chemie International …, 2020 - Wiley Online Library
Abstract The concept of 1, 3‐dipolar cycloadditions was presented by Rolf Huisgen 60 years
ago. Previously unknown reactive intermediates, for example azomethine ylides, were …

1, 3‐Dipolar cycloadditions of azides and alkynes: a universal ligation tool in polymer and materials science

JF Lutz - Angewandte Chemie International Edition, 2007 - Wiley Online Library
In 2001, Sharpless and co‐workers introduced “click” chemistry, a new approach in organic
synthesis that involves a handful of almost perfect chemical reactions. Among these carefully …

Organic azides

S Bräse, K Banert - Synthesis and Applications, 2010 - Wiley Online Library
This book is aimed at graduate students or researchers, who have basic knowledge in
organic chemistry and want to approach the field of organic azides from a historical …

Interweaving Visible‐Light and Iron Catalysis for Nitrene Formation and Transformation with Dioxazolones

JJ Tang, X Yu, Y Wang, Y Yamamoto… - Angewandte …, 2021 - Wiley Online Library
Herein, visible‐light‐driven iron‐catalyzed nitrene transfer reactions with dioxazolones for
intermolecular C (sp3)‐N, N= S, and N= P bond formation are described. These reactions …

Copper‐Catalyzed Intermolecular Trifluoromethylazidation of Alkenes: Convenient Access to CF3‐Containing Alkyl Azides

F Wang, X Qi, Z Liang, P Chen, G Liu - Angewandte Chemie, 2014 - Wiley Online Library
A novel copper‐catalyzed intermolecular trifluoromethylazidation of alkenes has been
developed under mild reaction conditions. A variety of CF3‐containing organoazides were …

Three‐component azidation of styrene‐type double bonds: light‐switchable behavior of a copper photoredox catalyst

G Fumagalli, PTG Rabet, S Boyd… - Angewandte Chemie …, 2015 - Wiley Online Library
Abstract [Cu (dap) 2] Cl effectively catalyzes azide addition from the Zhdankin reagent to
styrene‐type double bonds, and subsequent addition of a third component to the benzylic …

Staudinger ligation as a method for bioconjugation

SS Van Berkel, MB Van Eldijk… - Angewandte Chemie …, 2011 - Wiley Online Library
Abstract In 1919 the German chemist Hermann Staudinger was the first to describe the
reaction between an azide and a phosphine. It was not until recently, however, that Bertozzi …

Highly Robust Iron Catalyst System for Intramolecular C(sp3)−H Amidation Leading to γ‐Lactams

J Kweon, S Chang - Angewandte Chemie International Edition, 2021 - Wiley Online Library
Disclosed here is the use of an iron catalyst system for an intramolecular C− H amidation
toward γ‐lactam synthesis from dioxazolone precursors.(Phthalocyanine) FeIIICl was found …

A Combined Spectroscopic and Computational Study on the Mechanism of Iron-Catalyzed Aminofunctionalization of Olefins Using Hydroxylamine Derived N–O …

S Chatterjee, I Harden, G Bistoni… - Journal of the …, 2022 - ACS Publications
Herein, we study the mechanism of iron-catalyzed direct synthesis of unprotected
aminoethers from olefins by a hydroxyl amine derived reagent using a wide range of …

Manganese‐Catalyzed Oxidative Azidation of Cyclobutanols: Regiospecific Synthesis of Alkyl Azides by C C Bond Cleavage

R Ren, H Zhao, L Huan, C Zhu - … Chemie International Edition, 2015 - Wiley Online Library
A novel, manganese‐catalyzed oxidative azidation of cyclobutanols is described. A wide
range of primary, secondary, and tertiary alkyl azides were generated in synthetically useful …