After induction and specification in the ectoderm, at the border of the neural plate, the neural
crest (NC) population leaves its original territory through a delamination process. Soon …

Eph receptors constitute the largest family of tyrosine kinase receptors and, together with
their plasma-membrane-bound ephrin ligands, have many important functions during …

The vertebrate circulatory system is composed of arteries and veins. The functional and
pathological differences between these vessels have been assumed to reflect physiological …

Eph receptor tyrosine kinases and their cell-surface-bound ligands, the ephrins, regulate
axon guidance and bundling in the develo** brain, control cell migration and adhesion …

The gastrointestinal tract contains its own set of intrinsic neuroglial circuits—the enteric
nervous system (ENS)—which detects and responds to diverse signals from the …

The neural crest is a multipotent, migratory cell population that is unique to vertebrate
embryos and gives rise to many derivatives, ranging from the peripheral nervous system to …

▪ Abstract The Eph receptors are the largest known family of receptor tyrosine kinases.
Initially all of them were identified as orphan receptors without known ligands, and their …

The term 'vasculogenesis' refers to the earliest stages of vascular development, during
which vascular endothelial cell precursors undergo differentiation, expansion, and …

Ephrin-B2 is a transmembrane ligand that is specifically expressed on arteries but not veins
and that is essential for cardiovascular development. However, ephrin-B2 is also expressed …

The control of cell movement during development is essential for forming and stabilizing the
spatial organization of tissues and cell types. During initial steps of tissue patterning, distinct …