Vitamin D binding protein, total and free vitamin D levels in different physiological and pathophysiological conditions

DD Bikle, J Schwartz - Frontiers in endocrinology, 2019 - frontiersin.org
This review focuses on the biologic importance of the vitamin D binding protein (DBP) with
emphasis on its regulation of total and free vitamin D metabolite levels in various clinical …

Why should we measure free 25 (OH) vitamin D?

O Tsuprykov, X Chen, CF Hocher, R Skoblo… - The Journal of steroid …, 2018 - Elsevier
Vitamin D, either in its D 2 or D 3 form, is essential for normal human development during
intrauterine life, kidney function and bone health. Vitamin D deficiency has also been linked …

Current controversies: are free vitamin metabolite levels a more accurate assessment of vitamin D status than total levels?

DD Bikle, S Malmstroem… - … and Metabolism Clinics, 2017 - endo.theclinics.com
Circulating levels of 25-hydroxyvitamin D (25 (OH) D) are the most commonly used marker
for the assessment of vitamin D nutritional status. The main reason why 25 (OH) D levels are …

Vitamin D binding protein and 25-hydroxyvitamin D levels: emerging clinical applications

NK Jassil, A Sharma, D Bikle, X Wang - Endocrine Practice, 2017 - Elsevier
The precursor of the active form of vitamin D, 25-hydroxyvitamin D (25 (OH) D), is
recognized as the optimal indicator of vitamin D status. Vitamin D3 undergoes conversion …

Factors associated with early outcomes following standardised therapy in children with ulcerative colitis (PROTECT): a multicentre inception cohort study

JS Hyams, S Davis, DR Mack, B Boyle… - The Lancet …, 2017 - thelancet.com
Background Previous retrospective studies of paediatric ulcerative colitis have had limited
ability to describe disease progression and identify predictors of treatment response. In this …

[HTML][HTML] Links between disease severity, bacterial infections and oxidative stress in cystic fibrosis

S Galiniak, M Mołoń, M Rachel - Antioxidants, 2022 - mdpi.com
Cystic fibrosis (CF) is one of the most common, yet fatal genetic diseases in Caucasians.
The presence of a defective CF transmembrane conductance regulator and the massive …

Measurement of vitamin D for epidemiologic and clinical research: shining light on a complex decision

AMZ Jukic, AN Hoofnagle… - American journal of …, 2018 - academic.oup.com
Vitamin D is a fat-soluble vitamin that is synthesized in the skin with exposure to sunlight or
is ingested from dietary supplements or food. There has been a dramatic increase in …

The interplay between vitamin D status, subclinical inflammation, and prediabetes

A Arabi, D Nasrallah, S Mohsen, L Abugharbieh… - Heliyon, 2024 - cell.com
Vitamin D's role extends beyond classical calcium and phosphate homeostasis to
encompass a pivotal influence on immune modulation and metabolic health. The …

[HTML][HTML] Circulating biomarkers of antioxidant status and oxidative stress in people with cystic fibrosis: A systematic review and meta-analysis

AJ Causer, JK Shute, MH Cummings, AI Shepherd… - Redox biology, 2020 - Elsevier
Introduction Oxidative stress may play an important role in the pathophysiology of cystic
fibrosis (CF). This review aimed to quantify CF-related redox imbalances. Methods …

Impact of high-dose vitamin D3 on plasma free 25-hydroxyvitamin D concentrations and antimicrobial peptides in critically ill mechanically ventilated adults

JE Han, JA Alvarez, JL Jones, V Tangpricha, MA Brown… - Nutrition, 2017 - Elsevier
Objectives High-dose vitamin D 3 increases plasma total 25-hydroxyvitamin D [25 (OH) D] in
critically ill, ventilated patients; however, to our knowledge, the effect on plasma levels of …