[HTML][HTML] Diabetes mellitus: Classification, mediators, and complications; A gate to identify potential targets for the development of new effective treatments
Nowadays, diabetes mellitus has emerged as a significant global public health concern with
a remarkable increase in its prevalence. This review article focuses on the definition of …
a remarkable increase in its prevalence. This review article focuses on the definition of …
[HTML][HTML] Insulin signal transduction perturbations in insulin resistance
Type 2 diabetes mellitus is a widespread medical condition, characterized by high blood
glucose and inadequate insulin action, which leads to insulin resistance. Insulin resistance …
glucose and inadequate insulin action, which leads to insulin resistance. Insulin resistance …
Pathophysiology of human visceral obesity: an update
Excess intra-abdominal adipose tissue accumulation, often termed visceral obesity, is part of
a phenotype including dysfunctional subcutaneous adipose tissue expansion and ectopic …
a phenotype including dysfunctional subcutaneous adipose tissue expansion and ectopic …
Therapeutic potential of ginsenosides as an adjuvant treatment for diabetes
L Bai, J Gao, F Wei, J Zhao, D Wang… - Frontiers in …, 2018 - frontiersin.org
Ginseng, one of the oldest traditional Chinese medicinal herbs, has been used widely in
China and Asia for thousands of years. Ginsenosides extracted from ginseng, which is …
China and Asia for thousands of years. Ginsenosides extracted from ginseng, which is …
[HTML][HTML] Circulating inflammatory markers in polycystic ovary syndrome: a systematic review and metaanalysis
OBJECTIVE: To perform a review and metaanalysis of the studies evaluating the status of
serum inflammatory markers in women with polycystic ovary syndrome (PCOS). DESIGN …
serum inflammatory markers in women with polycystic ovary syndrome (PCOS). DESIGN …
[HTML][HTML] The major green tea polyphenol,(-)-epigallocatechin-3-gallate, inhibits obesity, metabolic syndrome, and fatty liver disease in high-fat–fed mice
In this study, we investigated the effects of the major green tea polyphenol,(-)-
epigallocatechin-3-gallate (EGCG), on high-fat–induced obesity, symptoms of the metabolic …
epigallocatechin-3-gallate (EGCG), on high-fat–induced obesity, symptoms of the metabolic …
Apelin stimulates glucose utilization in normal and obese insulin-resistant mice
C Dray, C Knauf, D Daviaud, A Waget, J Boucher… - Cell metabolism, 2008 - cell.com
Adipose tissue (AT) secretes several adipokines that influence insulin sensitivity and
potentially link obesity to insulin resistance. Apelin, a peptide present in different tissues, is …
potentially link obesity to insulin resistance. Apelin, a peptide present in different tissues, is …
Zinc and diabetes—clinical links and molecular mechanisms
J Jansen, W Karges, L Rink - The Journal of nutritional biochemistry, 2009 - Elsevier
Zinc is an essential trace element crucial for the function of more than 300 enzymes and it is
important for cellular processes like cell division and apoptosis. Hence, the concentration of …
important for cellular processes like cell division and apoptosis. Hence, the concentration of …
Stimulation of the hepatoportal nerve plexus with focused ultrasound restores glucose homoeostasis in diabetic mice, rats and swine
V Cotero, J Graf, H Miwa, Z Hirschstein… - Nature biomedical …, 2022 - nature.com
Peripheral neurons that sense glucose relay signals of glucose availability to integrative
clusters of neurons in the brain. However, the roles of such signalling pathways in the …
clusters of neurons in the brain. However, the roles of such signalling pathways in the …
Emerging roles for microRNAs in diabetic microvascular disease: novel targets for therapy
Y Zhang, X Sun, B Icli, MW Feinberg - Endocrinology Reviews, 2017 - academic.oup.com
Chronic, low-grade systemic inflammation and impaired microvascular function are critical
hallmarks in the development of insulin resistance. Accordingly, insulin resistance is a major …
hallmarks in the development of insulin resistance. Accordingly, insulin resistance is a major …