Neurovascular coupling and CO2 interrogate distinct vascular regulations

M Tournissac, E Chaigneau, S Pfister, AK Aydin… - Nature …, 2024‏ - nature.com
Neurovascular coupling (NVC), which mediates rapid increases in cerebral blood flow in
response to neuronal activation, is commonly used to map brain activation or dysfunction …

Pathophysiology of Chronic Hypercapnic Respiratory Failure

B Nanayakkara, S McNamara - Sleep Medicine Clinics, 2024‏ - sleep.theclinics.com
The major task of the respiratory system is to maintain adequate gas exchange, ensuring
sufficient oxygenation to fuel aerobic respiration while simultaneously maintaining a steady …

The hypoxic respiratory response of the pre-Bötzinger complex

J Khalilpour, HS Zangbar, MR Alipour, P Shahabi - Heliyon, 2024‏ - cell.com
Since the discovery of the pre-Bötzinger Complex (preBötC) as a crucial region for
generating the main respiratory rhythm, our understanding of its cellular and molecular …

[HTML][HTML] Functional evidence that S-nitroso-L-cysteine may be a candidate carotid body neurotransmitter

PM Getsy, GA Coffee, JN Bates, SM Baby… - …, 2025‏ - Elsevier
The primary objective of the present study is to provide further evidence that the
endogenous S-nitrosothiol, S-nitroso-L-cysteine (L-CSNO), plays an essential role in …

Loss-of-function of chemoreceptor neurons in the retrotrapezoid nucleus: what have we learned from it?

GMPR Souza, SBG Abbott - Respiratory Physiology & Neurobiology, 2024‏ - Elsevier
Central respiratory chemoreceptors are cells in the brain that regulate breathing in relation
to arterial pH and PCO 2. Neurons located at the retrotrapezoid nucleus (RTN) have been …

[HTML][HTML] Brainstem astrocytes regulate breathing and may affect arousal state in rats

M Bishop, S SheikhBahei - Physiology & Behavior, 2024‏ - Elsevier
Variations in arousal levels can impact respiratory patterns. The mechanisms by which
breathing behaviors can influence arousal state is not fully understood. In this study, we …

CO2/H+ detection in the body: a shared responsibility.

PL Katayama - Journal of Physiology, 2024‏ - search.ebscohost.com
The article in the Journal of Physiology discusses the detection of CO2/H+ levels in the body
by specialized cells known as chemoreceptors. These chemoreceptors, located in various …

Neurovascular coupling and briefCO2 interrogate distinct vascular regulations

M Tournissac, E Chaigneau, S Pfister, AK Aydin… - bioRxiv, 2024‏ - biorxiv.org
Neurovascular coupling (NVC), which mediates rapid increases in cerebral blood flow in
response to neuronal activation, is commonly used to map brain activation or dysfunction …

Do peripheral and central sites independently contribute to the CO2 stimulus for breathing?

HV Forster, MR Hodges - Journal of Physiology, 2024‏ - search.ebscohost.com
The article in the Journal of Physiology explores the contribution of peripheral and central
sites to the CO2 stimulus for breathing. SheikhBahaei et al. present evidence suggesting a …

Morphological deficits of glial cells in a transgenic mouse model for developmental stuttering

A Adeck, M Millwater, C Bragg, R Zhang… - bioRxiv, 2024‏ - biorxiv.org
Vocal production involves intricate neural coordination across various brain regions.
Stuttering, a common speech disorder, has genetic underpinnings, including mutations in …