Regulatory T cells in the treatment of disease

A Sharabi, MG Tsokos, Y Ding, TR Malek… - Nature reviews Drug …, 2018 - nature.com
Regulatory T (Treg) cells suppress inflammation and regulate immune system activity. In
patients with systemic or organ-specific autoimmune diseases or those receiving …

Regulatory T cells in multiple sclerosis and myasthenia gravis

KM Danikowski, S Jayaraman… - Journal of …, 2017 - Springer
Multiple sclerosis (MS) is a chronic debilitating disease of the central nervous system
primarily mediated by T lymphocytes with specificity to neuronal antigens in genetically …

Цитокины в патогенезе и лечении заболеваний человека

АС Симбирцев - 2018 - elibrary.ru
В монографии приведены сведения по роли цитокинов в регуляции физиологических
процессов, защитных реакций организма и в патогенезе иммунопатологических …

Regulatory T cell plasticity and stability and autoimmune diseases

R Qiu, L Zhou, Y Ma, L Zhou, T Liang, L Shi… - Clinical reviews in …, 2020 - Springer
Abstract CD4+ CD25+ regulatory T cells (Tregs) are a class of CD4+ T cells with
immunosuppressive functions that play a critical role in maintaining immune homeostasis …

Multiple sclerosis patients have reduced resting and increased activated CD4+CD25+FOXP3+T regulatory cells

ND Verma, AD Lam, C Chiu, GT Tran, BM Hall… - Scientific Reports, 2021 - nature.com
Resting and activated subpopulations of CD4+ CD25+ CD127loT regulatory cells (Treg) and
CD4+ CD25+ CD127+ effector T cells in MS patients and in healthy individuals were …

[HTML][HTML] Regulatory cells in multiple sclerosis: From blood to brain

L Calahorra, C Camacho-Toledano, MP Serrano-Regal… - Biomedicines, 2022 - mdpi.com
Multiple sclerosis (MS) is a chronic, autoimmune, and neurodegenerative disease of the
central nervous system (CNS) that affects myelin. The etiology of MS is unclear, although a …

Regulatory T cells and T helper 17 cells in viral infection

Z Wan, Z Zhou, Y Liu, Y Lai, Y Luo… - Scandinavian Journal …, 2020 - Wiley Online Library
CD4+ T cells are the central element of the adaptive immune responses and protect the
body from a variety of pathogens. Starting from naive cells, CD4+ T cells can differentiate …

Glutamate, T cells and multiple sclerosis

M Levite - Journal of Neural Transmission, 2017 - Springer
Glutamate is the major excitatory neurotransmitter in the nervous system, where it induces
multiple beneficial and essential effects. Yet, excess glutamate, evident in a kaleidoscope of …

The role of regulatory T cells in nervous system pathologies

SS Duffy, BA Keating, CJ Perera… - Journal of …, 2018 - Wiley Online Library
Regulatory T (Treg) cells are a special subpopulation of immunosuppressive T cells that are
essential for sustaining immune homeostasis. They maintain self‐tolerance, inhibit …

[HTML][HTML] Biochemical biomarkers for multiple sclerosis

J Maroto-García, A Martínez-Escribano… - Clinica Chimica …, 2023 - Elsevier
Introduction Multiple sclerosis (MS) is the most frequent demyelinating disease of the central
nervous system. Although there is currently no definite cure for MS, new therapies have …