Lipid nanoparticles for enhancing oral bioavailability

A Gangavarapu, LV Tapia-Lopez, B Sarkar… - Nanoscale, 2024 - pubs.rsc.org
In recent studies, lipid nanoparticles have attained attention as drug delivery systems owing
to their preeminent potential in achieving the desired bioavailability of Biopharmaceutics …

Chemistry and art of develo** lipid nanoparticles for biologics delivery: focus on development and scale-up

R John, J Monpara, S Swaminathan, R Kalhapure - Pharmaceutics, 2024 - mdpi.com
Lipid nanoparticles (LNPs) have gained prominence as primary carriers for delivering a
diverse array of therapeutic agents. Biological products have achieved a solid presence in …

Hierarchical Chitin Nanocrystal-Based 3D Printed Dual-Layer Membranes Hydrogels: A Dual Drug Delivery Nano-Platform for Periodontal Tissue Regeneration

DM Dos Santos, JI Moon, DS Kim, NJ Bassous… - ACS …, 2024 - ACS Publications
Periodontitis, a prevalent chronic inflammatory disease caused by bacteria, poses a
significant challenge to current treatments by merely slowing their progression. Herein, we …

Navigating the intricate in-vivo journey of lipid nanoparticles tailored for the targeted delivery of RNA therapeutics: a quality-by-design approach

E Haghighi, SS Abolmaali, A Dehshahri… - Journal of …, 2024 - Springer
RNA therapeutics, such as mRNA, siRNA, and CRISPR–Cas9, present exciting avenues for
treating diverse diseases. However, their potential is commonly hindered by vulnerability to …

Understanding the journey of biopolymeric nanoformulations for oral drug delivery: Conventional to advanced treatment approaches

A Sharma, N Jangra, D Dheer, SK Jha, G Gupta… - European Polymer …, 2024 - Elsevier
The oral route of drug administration offers a convenient, cost-efficient, and non-invasive
means of administering medications. Nevertheless, as newly developed active …

The landscape of nanoparticle-based siRNA delivery and therapeutic development

M Moazzam, M Zhang, A Hussain, X Yu, J Huang… - Molecular Therapy, 2024 - cell.com
Five small interfering RNA (siRNA)-based therapeutics have been approved by the Food
and Drug Administration (FDA), namely patisiran, givosiran, lumasiran, inclisiran, and …

Recent advances in surface decoration of nanoparticles in drug delivery

PD Ly, KN Ly, HL Phan, HHT Nguyen… - Frontiers in …, 2024 - frontiersin.org
Nanoparticulate delivery systems have been attracting attention in pharmaceutical sciences
for enhanced drug bioavailability and targeted delivery. Specifically, these systems can …

A review on modern characterization techniques for analysis of nanomaterials and biomaterials

RD Prasad, RS Prasad, RB Prasad… - ES Energy & …, 2024 - espublisher.com
This review is providing a comprehensive overview of essential genuine characterization
techniques for nanomaterial and biomaterials exist in various forms. Nanoscience and …

[HTML][HTML] Progress and promise of photoresponsive nanocarriers for precision drug delivery in cancer

NS Thakur, N Saleh, AF Khan, B Chakrabarty… - … of Photochemistry and …, 2024 - Elsevier
Controlled drug delivery has profoundly impacted medicine by facilitating precise
pharmacotherapy at targeted sites while mitigating adverse effects. Photoresponsive …

[HTML][HTML] Advancement in lipid-based nanocomposites for theranostic applications in lung carcinoma treatment

V Colaco, AA Roy, GARR Naik, A Mondal, S Mutalik… - OpenNano, 2024 - Elsevier
On a global scale, lung cancer remains a common malignancy and is largest cause of many
deaths related to cancer. Despite the significant advancements in lung cancer diagnostic …