Enzyme activity in nonaqueous media (eg conventional organic solvents) is typically lower
than in water by several orders of magnitude. There is a rising interest of develo** new …

Proteins are the molecular workhorses in a living organism. Their 3D structures are
animated by a multitude of equilibrium fluctuations and specific out-of-equilibrium motions …

One of the fundamental challenges of physical biology is to understand the relationship
between protein dynamics and function. At physiological temperatures, functional motions …

The increasing requirement to produce platform chemicals and fuels from renewable
sources means advances in biocatalysis are rapidly becoming a necessity. Biomass is …

Nonaqueous biocatalysis is rapidly becoming a desirable tool for chemical and fuel
synthesis in both the laboratory and industry. Similarly, ionic liquids are increasingly popular …

Water molecules play a number of critical roles in enzyme catalysis, including mass transfer
of substrates and products, nucleophilicity and proton transfer at the active site, and solvent …

Neutron scattering studies provide important information in structural biology that is not
accessible using other approaches. The uniqueness of the technique, and its …

The discovery by the Phoenix Lander of calcium and magnesium perchlorates in Martian
soil samples has fueled much speculation that flows of perchlorate brines might be the …

Extremozymes have gained considerable interest as they could meet industrial
requirements. Among these, SsoPox is a hyperthermostable enzyme isolated from the …

Conspectus Biomacromolecules, such as nucleic acids, proteins, and virus particles, are
persistent molecular entities with dimensions that exceed the range of their intermolecular …