Background The COVID-19 pandemic has caused significant stress and disruption for young
people, likely leading to alterations in their mental health and neurodevelopment. In this …

Introduction: Neurobiological dysfunction is associated with depression in children and
adolescents. While research in adult depression suggests that inflammation may underlie …

Pediatric internalizing disorders are prevalent and characterized by a maladaptive cognitive,
emotional response to a perceived stressor. The hypothesized effect of this response is …

Prenatal exposure to heightened maternal inflammation has been associated with adverse
neurodevelopmental outcomes, including atypical brain maturation and psychiatric illness …

Exposure to early life stress (ELS) increases the risk for develo** psychopathology;
however, the mechanisms underlying this association are not clear. In this study we …

Abstract Background and Hypothesis Low-grade neural and peripheral inflammation are
among the proposed pathophysiological mechanisms of schizophrenia. White matter …

Background Psoriasis is a chronic systemic inflammatory skin disease, coexisting with
depression in up to 25% of patients. Little is known about the drivers of comorbidity …

Elevated levels of systemic inflammation are associated with altered reward-related brain
function in ventral striatal areas of the brain like the nucleus accumbens (NAcc). In …

Maternal history of depression is a strong predictor of depression in offspring and linked to
structural and functional alterations in the develo** brain. However, very little work has …

Adolescence is often characterized by sleep disturbances that can affect the development of
white matter tracts implicated in affective and cognitive regulation, including the cingulate …