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[HTML][HTML] Consequences of disturbing manganese homeostasis
Manganese (Mn) is an essential trace element with unique functions in the body; it acts as a
cofactor for many enzymes involved in energy metabolism, the endogenous antioxidant …
cofactor for many enzymes involved in energy metabolism, the endogenous antioxidant …
Tumor microenvironment-responsive manganese-based nanomaterials for cancer treatment
Tumor microenvironment (TME), which characteristically displays hypoxia,
immunosuppression, reprogramming metabolism and mild acidity, has been considered as …
immunosuppression, reprogramming metabolism and mild acidity, has been considered as …
The role of manganese dysregulation in neurological disease: emerging evidence
Manganese is an essential trace metal. The dysregulation of manganese seen in a broad
spectrum of neurological disorders reflects its importance in brain development and key …
spectrum of neurological disorders reflects its importance in brain development and key …
Ferroptosis as a mechanism of non-ferrous metal toxicity
Ferroptosis is a recently discovered form of regulated cell death, implicated in multiple
pathologies. Given that the toxicity elicited by some metals is linked to alterations in iron …
pathologies. Given that the toxicity elicited by some metals is linked to alterations in iron …
Trace elements in Alzheimer's disease and dementia: The current state of knowledge
M Tyczyńska, M Gędek, A Brachet, W Stręk… - Journal of clinical …, 2024 - mdpi.com
Changes in trace element concentrations are being wildly considered when it comes to
neurodegenerative disorders, such as Alzheimer's disease and Parkinson's disease. This …
neurodegenerative disorders, such as Alzheimer's disease and Parkinson's disease. This …
Microglial activation in metal neurotoxicity: impact in neurodegenerative diseases
MI Martínez-Hernández… - BioMed Research …, 2023 - Wiley Online Library
Neurodegenerative processes encompass a large variety of diseases with different
pathological patterns and clinical features, such as Alzheimer's and Parkinson's diseases …
pathological patterns and clinical features, such as Alzheimer's and Parkinson's diseases …
Alzheimer's disease: the role of extrinsic factors in its development, an investigation of the environmental enigma
In the realm of Alzheimer's disease, the most prevalent form of dementia, the impact of
environmental factors has ignited intense curiosity due to its substantial burden on global …
environmental factors has ignited intense curiosity due to its substantial burden on global …
[HTML][HTML] Sesamol alleviates manganese-induced neuroinflammation and cognitive impairment via regulating the microglial cGAS-STING/NF-κB pathway
Toxic effects of excessive manganese (Mn) from occupational or environmental exposure
cause harm to human health. Excessive Mn exposure is intimately associated with …
cause harm to human health. Excessive Mn exposure is intimately associated with …
Baseline maps of potentially toxic elements in the soils of Garhwal Himalayas, India: Assessment of their eco‐environmental and human health risks
Geochemical map** is frequently used to identify the regions of the Planet with critical
chemical elements and their natural or anthropogenic sources. In order to understand …
chemical elements and their natural or anthropogenic sources. In order to understand …
Manganese and related neurotoxic pathways: A potential therapeutic target in neurodegenerative diseases
Neurodegenerative diseases comprise a group of disorders characterized by progressive
loss of neurons over a period of time due to various factors such as oxidative stress …
loss of neurons over a period of time due to various factors such as oxidative stress …