Oxidative stress: the role of antioxidant phytochemicals in the prevention and treatment of diseases

A Muscolo, O Mariateresa, T Giulio… - International journal of …, 2024‏ - mdpi.com
Oxidative stress, characterized by an imbalance favouring oxidants over antioxidants, is a
key contributor to the development of various common diseases. Counteracting these …

Advances in pathogenesis and therapeutic strategies for osteoporosis

S Song, Y Guo, Y Yang, D Fu - Pharmacology & therapeutics, 2022‏ - Elsevier
Osteoporosis, is the most common bone disorder worldwide characterized by low bone
mineral density, leaving affected bones vulnerable to fracture. Bone homeostasis depends …

[Retracted] Ellagic Acid: A Review on Its Natural Sources, Chemical Stability, and Therapeutic Potential

J Sharifi-Rad, C Quispe, CMS Castillo… - Oxidative medicine …, 2022‏ - Wiley Online Library
Ellagic acid (EA) is a bioactive polyphenolic compound naturally occurring as secondary
metabolite in many plant taxa. EA content is considerable in pomegranate (Punica granatum …

[HTML][HTML] Polyphenol-mediated gut microbiota modulation: toward prebiotics and further

MC Rodríguez-Daza, EC Pulido-Mateos… - Frontiers in …, 2021‏ - frontiersin.org
The genome of gut microbes encodes a collection of enzymes whose metabolic functions
contribute to the bioavailability and bioactivity of unabsorbed (poly) phenols. Datasets from …

[HTML][HTML] Regulation of intestinal barrier function by microbial metabolites

S Ghosh, CS Whitley, B Haribabu, VR Jala - Cellular and molecular …, 2021‏ - Elsevier
The human gastrointestinal tract (GI) harbors a diverse population of microbial life that
continually shapes host pathophysiological responses. Despite readily available abundant …

The role of iron in host–microbiota crosstalk and its effects on systemic glucose metabolism

J Mayneris-Perxachs, JM Moreno-Navarrete… - Nature Reviews …, 2022‏ - nature.com
Iron is critical for the appearance and maintenance of life on Earth. Almost all organisms
compete or cooperate for iron acquisition, demonstrating the importance of this essential …

Enhancement of the gut barrier integrity by a microbial metabolite through the Nrf2 pathway

R Singh, S Chandrashekharappa, SR Bodduluri… - Nature …, 2019‏ - nature.com
The importance of gut microbiota in human health and pathophysiology is undisputable.
Despite the abundance of metagenomics data, the functional dynamics of gut microbiota in …

[HTML][HTML] Trace metals and animal health: Interplay of the gut microbiota with iron, manganese, zinc, and copper

EAB Pajarillo, E Lee, DK Kang - Animal Nutrition, 2021‏ - Elsevier
Metals such as iron, manganese, copper, and zinc are recognized as essential trace
elements. These trace metals play critical roles in development, growth, and metabolism …

A pharmacological update of ellagic acid

JL Ríos, RM Giner, M Marín, MC Recio - Planta medica, 2018‏ - thieme-connect.com
Ellagic acid is a common metabolite present in many medicinal plants and vegetables. It is
present either in free form or as part of more complex molecules (ellagitannins), which can …

An overview on the role of dietary phenolics for the treatment of cancers

PG Anantharaju, PC Gowda, MG Vimalambike… - Nutrition journal, 2016‏ - Springer
Plant derived phenolic compounds have been shown to inhibit the initiation and progression
of cancers by modulating genes regulating key processes such as:(a) oncogenic …