Unveiling heterogeneity in MSCs: Exploring marker-based strategies for defining MSC subpopulations

S Chen, B Liang, J Xu - Journal of Translational Medicine, 2024 - Springer
Mesenchymal stem/stromal cells (MSCs) represent a heterogeneous cell population
distributed throughout various tissues, demonstrating remarkable adaptability to …

Unraveling the Dynamics of Estrogen and Progesterone Signaling in the Endometrium: An Overview

ID Da Silva, V Wuidar, M Zielonka, C Pequeux - Cells, 2024 - pmc.ncbi.nlm.nih.gov
The endometrium is crucial for the perpetuation of human species. It is a complex and
dynamic tissue lining the inner wall of the uterus, regulated throughout a woman's life based …

Endometrial stem/progenitor cells–their role in endometrial repair and regeneration

FL Cousins, CE Filby, CE Gargett - Frontiers in Reproductive Health, 2022 - frontiersin.org
The human endometrium is a remarkable tissue, undergoing~ 450 cycles of proliferation,
differentiation, shedding (menstruation), repair, and regeneration over a woman's …

[HTML][HTML] Exploiting the features of short peptides to recognize specific cell surface markers

M Buonocore, M Grimaldi, A Santoro, V Covelli… - International Journal of …, 2023 - mdpi.com
Antibodies are the macromolecules of choice to ensure specific recognition of biomarkers in
biological assays. However, they present a range of shortfalls including a relatively high …

Xenogenic application of human placenta-derived mesenchymal stromal cells in a porcine large animal model

N Harland, J Knoll, B Amend, T Abruzzese… - Cell …, 2024 - journals.sagepub.com
In animal models, cell therapies for different diseases or injuries have been very successful.
Preclinical studies with cells aiming at a stroke, heart attack, and other emergency situations …

The dual role of SUSD2 in cancer development

H Bai, N **an, F Zhao, Y Zhou, S Qin - European Journal of Pharmacology, 2024 - Elsevier
Sushi domain-containing protein 2 (SUSD2, also known as the complement control protein
domain) is a representative and vital protein in the SUSD protein family involved in many …

TLR4 modulates senescence and paracrine action in placental mesenchymal stem cells via inhibiting hedgehog signaling pathway in preeclampsia

Y Zhong, Y Zhang, W Liu, Y Zhao… - … Medicine and Cellular …, 2022 - Wiley Online Library
Preeclampsia (PE) is a heterogeneous disease closely associated with the accelerated
senescence of the placentas. Placental mesenchymal stem cells (PMSCs) modulate …

Stromal cells of the endometrium and decidua: in search of a name and an identity

MJ Ruiz-Magaña, T Llorca… - Biology of …, 2022 - academic.oup.com
Human endometrial and decidual stromal cells are the same cells in different environments
(nonpregnancy and pregnancy, respectively). Although some authors consider decidual …

[HTML][HTML] The fate of human SUSD2+ endometrial mesenchymal stem cells during decidualization

TG Sparovec, UR Markert, P Reif, W Schoell, G Moser… - Stem Cell Research, 2022 - Elsevier
Regeneration of the endometrial stromal compartment in premenopausal women is likely
maintained by the perivascular endometrial mesenchymal stem/stromal cells (eMSC) …

The potential of mesenchymal stem cells to induce immune tolerance to allogeneic transplants

S Yu, J Lu - Transplant Immunology, 2023 - Elsevier
Organ allograft transplantation is an effective treatment plan for patients with organ failure.
Although the application of continuous immunosuppressants makes successful allograft …