Mesenchymal stromal/stem cell (MSC)-derived exosomes in clinical trials
A Lotfy, NM AboQuella, H Wang - Stem Cell Research & Therapy, 2023 - Springer
Mesenchymal stromal/stem cells (MSCs) are widely utilized in cell therapy because of their
robust immunomodulatory and regenerative properties. Their paracrine activity is one of the …
robust immunomodulatory and regenerative properties. Their paracrine activity is one of the …
Advances in extracellular vesicle nanotechnology for precision theranostics
Q Wu, S Fu, H ** review
Background Exosomes, nano-sized extracellular vesicles, have emerged as a promising
tool for the diagnosis and treatment of various intractable diseases, including chronic …
tool for the diagnosis and treatment of various intractable diseases, including chronic …
[HTML][HTML] Exosomes, autophagy and ER stress pathways in human diseases: Cross-regulation and therapeutic approaches
Exosomal release pathway and autophagy together maintain homeostasis and survival of
cells under stressful conditions. Autophagy is a catabolic process through which cell entities …
cells under stressful conditions. Autophagy is a catabolic process through which cell entities …
Updated living systematic review and meta-analysis of controlled trials of mesenchymal stromal cells to treat COVID-19: a Framework for Accelerated Synthesis of Trial …
AM Kirkham, AJM Bailey, M Monaghan… - Stem cells …, 2022 - academic.oup.com
Abstract Background Mesenchymal stromal cells (MSCs) may reduce mortality in patients
with COVID-19; however, early evidence is based on few studies with marked interstudy …
with COVID-19; however, early evidence is based on few studies with marked interstudy …
Mesenchymal stem cell-derived extracellular vesicles for therapeutic use and in bioengineering applications
Extracellular vesicles (EVs) are small lipid bilayer-delimited particles that are naturally
released from cells into body fluids, and therefore can travel and convey regulatory functions …
released from cells into body fluids, and therefore can travel and convey regulatory functions …
Extracellular vesicle-transmitted miR-671-5p alleviates lung inflammation and injury by regulating the AAK1/NF-κB axis
J Lian, X Zhu, J Du, B Huang, F Zhao, C Ma, R Guo… - Molecular Therapy, 2023 - cell.com
Mesenchymal stem cells regulate remote intercellular signaling communication via their
secreted extracellular vesicles. Here, we report that menstrual blood-derived stem cells …
secreted extracellular vesicles. Here, we report that menstrual blood-derived stem cells …
COVID-19 inflammation and implications in drug delivery
Growing evidence indicates that hyperinflammatory syndrome and cytokine storm observed
in COVID-19 severe cases are narrowly associated with the disease's poor prognosis …
in COVID-19 severe cases are narrowly associated with the disease's poor prognosis …
A Review of Extracellular Vesicles in COVID‐19 Diagnosis, Treatment, and Prevention
P Su, Y Wu, F **e, Q Zheng, L Chen, Z Liu… - Advanced …, 2023 - Wiley Online Library
The 2019 novel coronavirus disease (COVID‐19) pandemic caused by severe acute
respiratory syndrome coronavirus 2 (SARS‐CoV‐2) is ongoing, and has necessitated …
respiratory syndrome coronavirus 2 (SARS‐CoV‐2) is ongoing, and has necessitated …