ST-segment elevation myocardial infarction (STEMI) is the most acute manifestation of
coronary artery disease and is associated with great morbidity and mortality. A complete …

The presence of macrophages within the plaque is a defining hallmark of atherosclerosis.
Macrophages are exposed to various microenvironments such as oxidized lipids and …

Intake of hemoglobin by the hemoglobin-haptoglobin receptor CD163 leads to a distinct
alternative non–foam cell antiinflammatory macrophage phenotype that was previously …

Atherosclerosis is the most common form of vascular disease and constitutes the major
cause of death, with 17.5 million related deaths annually (31% of global mortality). 1 …

Rheumatoid arthritis (RA) has long been associated with increased cardiovascular risk, but
despite substantial improvements in disease management, mortality remains high …

Background Intraplaque haemorrhage (IPH) drives atherosclerosis progression and is a key
imaging biomarker of unstable plaques. Non-invasive and sensitive monitoring of IPH is …

There is a common misperception in the cardiology community that most acute coronary
events arise from ruptures of mildly stenotic plaques. This notion has emanated from …

Objectives: This study sought to conduct a systematic review and meta-analysis to determine
precise estimates of the predictive value of carotid intraplaque hemorrhage (IPH) as …

Background and Purpose—For symptomatic patients with carotid artery stenosis, the risk
benefit for surgical intervention may vary among patient groups. Various modalities of …

Objectives: The goal of this study was to evaluate the feasibility of [18F] Galacto-RGD
positron emission tomography (PET)/computed tomography (CT) imaging of αvβ3 …