A 2020 view of tension-based cortical morphogenesis

DC Van Essen - Proceedings of the National Academy of …, 2020 - National Acad Sciences
Mechanical tension along the length of axons, dendrites, and glial processes has been
proposed as a major contributor to morphogenesis throughout the nervous system [DC Van …

Imaging flies by fluorescence microscopy: principles, technologies, and applications

S Dunst, P Tomancak - Genetics, 2019 - academic.oup.com
The development of fluorescent labels and powerful imaging technologies in the last two
decades has revolutionized the field of fluorescence microscopy, which is now widely used …

[HTML][HTML] The physics of active polymers and filaments

RG Winkler, G Gompper - The journal of chemical physics, 2020 - pubs.aip.org
Active matter agents consume internal energy or extract energy from the environment for
locomotion and force generation. Already, rather generic models, such as ensembles of …

Newfound sex differences in axonal structure underlie differential outcomes from in vitro traumatic axonal injury

JP Dollé, A Jaye, SA Anderson, H Ahmadzadeh… - Experimental …, 2018 - Elsevier
Since traumatic axonal injury (TAI) is implicated as a prominent pathology of concussion, we
examined potential sex differences in axon structure and responses to TAI. Rat and human …

Tangentially driven active polar linear polymers—An analytical study

CA Philipps, G Gompper, RG Winkler - The Journal of Chemical …, 2022 - pubs.aip.org
The conformational and dynamical properties of isolated flexible active polar linear polymers
(APLPs) are studied analytically. The APLPs are modeled as Gaussian bead-spring linear …

Topological chaos in active nematics

AJ Tan, E Roberts, SA Smith, UA Olvera, J Arteaga… - Nature Physics, 2019 - nature.com
Active nematics are out-of-equilibrium fluids composed of rod-like subunits, which can
generate large-scale, self-driven flows. We examine a microtubule-kinesin-based active …

Moonlighting motors: kinesin, dynein, and cell polarity

W Lu, VI Gelfand - Trends in cell biology, 2017 - cell.com
In addition to their well-known role in transporting cargoes in the cytoplasm, microtubule
motors organize their own tracks–the microtubules. While this function is mostly studied in …

Dynamics of active polar ring polymers

CA Philipps, G Gompper, RG Winkler - Physical Review E, 2022 - APS
The conformational and dynamical properties of isolated semiflexible active polar ring
polymers are investigated analytically. A ring is modeled as a continuous Gaussian polymer …

[HTML][HTML] The developmental biology of kinesins

MJ Konjikusic, RS Gray, JB Wallingford - Developmental biology, 2021 - Elsevier
Kinesins are microtubule-based motor proteins that are well known for their key roles in cell
biological processes ranging from cell division, to intracellular transport of mRNAs, proteins …

Cytoplasmic stirring by active carpets

B Chakrabarti, M Rachh, SY Shvartsman… - Proceedings of the …, 2024 - pnas.org
Large cells often rely on cytoplasmic flows for intracellular transport, maintaining
homeostasis, and positioning cellular components. Understanding the mechanisms of these …