Establishing electron diffraction in chemical crystallography

T Gruene, JJ Holstein, GH Clever… - Nature Reviews Chemistry, 2021 - nature.com
The emerging field of 3D electron diffraction (3D ED) opens new opportunities for structure
determination from sub-micrometre-sized crystals. Although the foundations of this …

Diberyllocene, a stable compound of Be (I) with a Be–Be bond

JT Boronski, AE Crumpton, LL Wales, S Aldridge - Science, 2023 - science.org
The complex diberyllocene, CpBeBeCp (Cp, cyclopentadienyl anion), has been the subject
of numerous chemical investigations over the past five decades yet has eluded experimental …

A nucleophilic beryllyl complex via metathesis at [Be–Be]2+

JT Boronski, AE Crumpton, AF Roper, S Aldridge - Nature Chemistry, 2024 - nature.com
Owing to its high toxicity, the chemistry of element number four, beryllium, is poorly
understood. However, as the lightest elements provide the basis for fundamental models of …

[HTML][HTML] 1, 4, 9, 9-tetramethyloctahydro-4, 7-(epoxymethano) azulen-5 (1H)-one, a natural product as a potential inhibitor of COVID-19: Extraction, crystal structure, and …

Y El Bakri, SK Mohamed, K Saravanan… - Journal of King Saud …, 2023 - Elsevier
In the present work, we describe the extraction of a natural product namely 1, 4, 9, 9-
tetramethyloctahydro-4, 7-(epoxymethano) azulen-5 (1H)-one, and its structure was …

X-ray constrained wavefunctions based on Hirshfeld atoms. I. Method and review

ML Davidson, S Grabowsky, D Jayatilaka - Structural Science, 2022 - journals.iucr.org
The X-ray constrained wavefunction (XCW) procedure for obtaining an experimentally
reconstructed wavefunction from X-ray diffraction data is reviewed. The two-center …

A solid noncovalent organic double-helix framework catalyzes asymmetric [6+ 4] cycloaddition

T Zheng, N Nöthling, Z Wang, B Mitschke, M Leutzsch… - Science, 2024 - science.org
Whereas [4+ 2] cycloadditions are among the most powerful tools in the chemist's synthetic
arsenal, controlling reactivity and selectivity of [6+ 4] cycloadditions has proven to be …

Exploration of isoxazole analogs: Synthesis, COX inhibition, anticancer screening, 3D multicellular tumor spheroids, and molecular modeling

M Hawash, S Abdallah, M Abudayyak… - European Journal of …, 2024 - Elsevier
In this study, a new series of Isoxazole-carboxamide derivatives were synthesized and
characterized via HRMS, 1 H-, 13 C APT-NMR, and MicroED. The findings revealed that …

Isolation, bonding and reactivity of a monomeric stibine oxide

JS Wenger, M Weng, GN George, TC Johnstone - Nature Chemistry, 2023 - nature.com
In contrast to phosphine oxides and arsine oxides, which are common and exist as stable
monomeric species featuring the corresponding pnictoryl functional group (Pn= O/Pn+–O−; …

Molecular design boosts hydrolytic stability of diisopropanolamine boronic ester hydrogel for long-term drug release

H Kang, Z Xu, Y Huang, K Liu, W Wei, L Xu… - Chemistry of …, 2024 - ACS Publications
Boronic ester hydrogels are widely used in biomedicine for their stimulus responsiveness to
multiple disease-related triggers. However, their applicability is limited by its low hydrolytic …

Self-assembly of new cobalt complexes based on [Co (SCN)4], synthesis, empirical, antioxidant activity, and quantum theory investigations

A Ferchichi, J Makhlouf, Y El Bakri, K Saravanan… - Scientific Reports, 2022 - nature.com
The cobalt (II) complexes have been synthesized from the reaction of the cationic entities (3,
4-dimethylaniline (1) and histamine (2)) with metallic salt CoCl2⋅ 6H2O and thiocyanate ion …