Three classes of methionine sulfoxide reductases are known: MsrA and MsrB which are
implicated stereo-selectively in the repair of protein oxidized on their methionine residues; …

The sulfur-containing amino acid methionine (Met) in its free and amino acid residue forms
can be readily oxidized to the R and S diastereomers of methionine sulfoxide (MetO) …

Control of the sexually transmitted infection gonorrhea is a major public health challenge,
due to the recent emergence of multidrug resistant strains of Neisseria gonorrhoeae, and …

Enzymatic Nsingle bondN bond formation is rare. Herein, the mechanism for the N-
nitrosation from N δ-hydroxy-N ω-hydroxy-N ω-methyl-L-arginine (L-HMA) catalyzed by …

Sulfoxides and selenoxides oxidize thiols to disulfides while being reduced back to sulfides
and selenides. While the reduction mechanism of sulfoxides to sulfides has been thoroughly …

Neisseria meningitidis, an obligate pathogenic bacterium in humans, has acquired different
defense mechanisms to detect and fight the oxidative stress generated by the host's defense …

Aminoacyl-tRNA synthetases (aaRSs) are essential enzymes that remarkable facilitate the
aminoacylation process during translation. With a high fidelity, the mischarged tRNA is …

The catalytic mechanism of MsrA in Mycobacterium tuberculosis, in which S-methionine
sulfoxide (Met-O) is reduced to methionine (Met), has been investigated using docking …

The reactivity of disulfide and diselenide derivatives towards F− and CN− nucleophiles has
been investigated by means of B3PW91/6‐311+ G (2df, p) calculations. This theoretical …

MsrB. In particular, they acknowledged that the formation of a sulfonium cation along the
catalytic pathway was convincingly1 shown. Incidentally, they noted that our subsequent …