Charged-particle therapy in cancer: clinical uses and future perspectives

M Durante, R Orecchia, JS Loeffler - Nature Reviews Clinical Oncology, 2017 - nature.com
Radiotherapy with high-energy charged particles has become an attractive therapeutic
option for patients with several tumour types because this approach better spares healthy …

A concise review on cancer treatment methods and delivery systems

E Bidram, Y Esmaeili, H Ranji-Burachaloo… - Journal of Drug Delivery …, 2019 - Elsevier
The ultimate purpose of current cancer research is to develop a comprehensive treatment for
cancer. Recent studies have shown an increased interest in investigating the capacity of …

A critical review of recent developments in radiotherapy for non-small cell lung cancer

S Baker, M Dahele, FJ Lagerwaard, S Senan - Radiation oncology, 2016 - Springer
Lung cancer is the leading cause of cancer mortality, and radiotherapy plays a key role in
both curative and palliative treatments for this disease. Recent advances include stereotactic …

Dose calculation algorithms for external radiation therapy: an overview for practitioners

F De Martino, S Clemente, C Graeff, G Palma, L Cella - Applied sciences, 2021 - mdpi.com
Featured Application Radiation therapy treatment planning. Abstract Radiation therapy (RT)
is a constantly evolving therapeutic technique; improvements are continuously being …

Thoracic radiation normal tissue injury

CB Simone II - Seminars in radiation oncology, 2017 - Elsevier
Thoracic malignancies are often a difficult group of tumors to treat definitively as the
radiation doses needed to achieve a high probability for tumor control are often associated …

Recognizing radiation therapy–related complications in the chest

MF Benveniste, D Gomez, BW Carter… - Radiographics, 2019 - pubs.rsna.org
Radiation therapy is one of the cornerstones for the treatment of thoracic malignancies.
Although advances in radiation therapy technology have improved the delivery of radiation …

Radiation combined with immune checkpoint inhibitors for unresectable locally advanced non-small cell lung cancer: synergistic mechanisms, current state …

L Wu, Z Zhang, M Bai, Y Yan, J Yu, Y Xu - Cell Communication and …, 2023 - Springer
Until the advent of immune checkpoint inhibitors (ICIs), definitive radiotherapy (RT)
concurrently with chemotherapy was recommended for unresectable, locally advanced non …

Proton beam radiotherapy and concurrent chemotherapy for unresectable stage III non–small cell lung cancer: final results of a phase 2 study

JY Chang, V Verma, M Li, W Zhang, R Komaki… - JAMA …, 2017 - jamanetwork.com
Importance Proton beam radiotherapy (PBT) has the potential to reduce toxic effects in the
definitive management of locally advanced non–small cell lung cancer (NSCLC), but long …

Quantitative assessment of 3D dose rate for proton pencil beam scanning FLASH radiotherapy and its application for lung hypofractionation treatment planning

M Kang, S Wei, JI Choi, CB Simone, H Lin - Cancers, 2021 - mdpi.com
Simple Summary As pencil beam scanning (PBS) proton therapy delivers doses via spot-
scanning, the dose rate quantification is very different from the electron and scattering proton …

“Radiobiology of Proton Therapy”: Results of an international expert workshop

A Lühr, C von Neubeck, J Pawelke, A Seidlitz… - Radiotherapy and …, 2018 - Elsevier
The physical properties of proton beams offer the potential to reduce toxicity in tumor-
adjacent normal tissues. Toward this end, the number of proton radiotherapy facilities has …