[HTML][HTML] B cells and tertiary lymphoid structures in tumors: immunity cycle, clinical impact, and therapeutic applications

X Wu, Q Huang, X Chen, B Zhang, J Liang… - Theranostics, 2025 - pmc.ncbi.nlm.nih.gov
Tumorigenesis involves a multifaceted and heterogeneous interplay characterized by
perturbations in individual immune surveillance. Tumor-infiltrating lymphocytes, as …

[HTML][HTML] Oxysterols in tumor immune microenvironment (TIME)

Y Liu, J Qin, X Li, G Wu - The Journal of Steroid Biochemistry and Molecular …, 2024 - Elsevier
Oxysterols are compounds generated through oxidative reactions involving cholesterol and
other steroid molecules. They play a crucial role in the tumor immune microenvironment by …

CD63 sorts cholesterol into endosomes for storage and distribution via exosomes

R Palmulli, M Couty, MC Piontek, M Ponnaiah… - Nature Cell …, 2024 - nature.com
Extracellular vesicles such as exosomes are now recognized as key players in intercellular
communication. Their role is influenced by the specific repertoires of proteins and lipids …

Endoscopic surgery affects the gut microbiota and its metabolism in breast cancer patients

J Li, F Gao, R Li, Z Chen, G Chen, P Fan… - Frontiers in …, 2025 - frontiersin.org
Background Despite the advantages of endoscopic surgery in reducing trauma and
enhancing recovery for breast cancer patients, its impact on gut microbiota, which is crucial …

New insights into the role of tetraspanin 6, 7, and 8 in physiology and pathology

M Mrozowska, T Górnicki, M Olbromski… - Cancer …, 2024 - Wiley Online Library
Background The tetraspanin (TSPAN) family comprises 33 membrane receptors involved in
various physiological processes in humans. Tetrasapanins are surface proteins expressed …

[HTML][HTML] GWASTool: A web pipeline for detecting SNP-phenotype associations

X Wang, B **n, M Guo, G Yu, J Wang - Fundamental Research, 2024 - Elsevier
The genome-wide association study (GWAS) aims to detect associations between individual
single nucleotide polymorphisms (SNPs) or SNP interactions and phenotypes to decipher …

Integrated bioinformatics analysis reveals the bidirectional effects of TSPAN6 for cisplatin resistance in lung cancer

Z Fang, J Bai - Chemical Biology & Drug Design, 2024 - Wiley Online Library
Cisplatin‐based chemotherapy is frequently employed as the primary therapeutic approach
for advanced lung cancer. Nevertheless, a significant proportion of patients may develop …

[HTML][HTML] Exploring oxysterols and protein carbonylation in cervicovaginal secretions as biomarkers for cervical cancer development

B Kose, S Erkanlı, A Koçak, C Guzel, T Luider… - Advances in Redox …, 2024 - Elsevier
Cervical cancer, a major global health issue and the fourth most common cancer among
women, is strongly linked to Human Papillomavirus (HPV) infection. Emerging evidence …

[HTML][HTML] Protocol for transcutaneous tumor photolabeling to track immune cells in vivo using Kaede mice

I Dean, BC Kennedy, Z Li, F Berditchevski, DR Withers - STAR protocols, 2024 - Elsevier
Preclinical tumor models have advanced our understanding of the tumor microenvironment.
However, the temporal dynamics of cellular recruitment and retention within these models is …

Oxysterols as Biomarkers of Aging and Disease

IHK Dias, H Shokr - Implication of Oxysterols and Phytosterols in Aging …, 2023 - Springer
Oxysterols derive from either enzymatic or non-enzymatic oxidation of cholesterol. Even
though they are produced as intermediates of bile acid synthesis pathway, they are …