The role of protein corona on nanodrugs for organ-targeting and its prospects of application

S Wang, J Zhang, H Zhou, YC Lu, X **, L Luo… - Journal of Controlled …, 2023 - Elsevier
Nowadays, nanodrugs become a hotspot in the high-end medical field. They have the ability
to deliver drugs to reach their destination more effectively due to their unique properties and …

[HTML][HTML] Translational challenges and prospective solutions in the implementation of biomimetic delivery systems

Z Wang, X Wang, W Xu, Y Li, R Lai, X Qiu, X Chen… - Pharmaceutics, 2023 - mdpi.com
Biomimetic delivery systems (BDSs), inspired by the intricate designs of biological systems,
have emerged as a groundbreaking paradigm in nanomedicine, offering unparalleled …

Real-time optical tracking of protein corona formation on single nanoparticles in serum

M Dolci, Y Wang, SW Nooteboom… - ACS …, 2023 - ACS Publications
The formation of a protein corona, where proteins spontaneously adhere to the surface of
nanomaterials in biological environments, leads to changes in their physicochemical …

[HTML][HTML] Polymeric nanoparticles and nanogels: how do they interact with proteins?

A Sadeghi, S PourEskandar, E Askari, M Akbari - Gels, 2023 - mdpi.com
Polymeric nanomaterials, nanogels, and solid nanoparticles can be fabricated using single
or double emulsion methods. These materials hold great promise for various biomedical …

[HTML][HTML] Accelerating therapeutic protein design with computational approaches toward the clinical stage

Z Chen, X Wang, X Chen, J Huang, C Wang… - Computational and …, 2023 - Elsevier
Therapeutic protein, represented by antibodies, is of increasing interest in human medicine.
However, clinical translation of therapeutic protein is still largely hindered by different …

[HTML][HTML] Erythrocyte− cancer hybrid membrane-coated reduction-sensitive nanoparticles for enhancing chemotherapy efficacy in breast cancer

S Rezaei, RF de Araújo Júnior, ILG da Silva… - Biomaterials …, 2023 - Elsevier
Cell-membrane-coated biomimetic nanoparticles (NPs) have attracted great attention due to
their prolonged circulation time, immune escape mechanisms and homotypic targeting …

Protein Aggregation on Metal Oxides Governs Catalytic Activity and Cellular Uptake

R Nißler, L Dennebouy, A Gogos, LRH Gerken… - Small, 2024 - Wiley Online Library
Engineering of catalytically active inorganic nanomaterials holds promising prospects for
biomedicine. Catalytically active metal oxides show applications in enhancing wound …

Optimal delivery strategies for nanoparticle-mediated mRNA delivery

X Li, X Guo, M Hu, R Cai, C Chen - Journal of Materials Chemistry B, 2023 - pubs.rsc.org
Messenger RNA (mRNA) has emerged as a new and efficient agent for the treatment of
various diseases. The success of lipid nanoparticle-mRNA against the novel coronavirus …

Homologous-adhering/targeting cell membrane-and cell-mediated delivery systems: a cancer-catch-cancer strategy in cancer therapy

C Liu, J Gao, Y Cheng, S Zhang… - Regenerative …, 2024 - academic.oup.com
Low tumor enrichment remains a serious and urgent problem for drug delivery in cancer
therapy. Accurate targeting to tumor site is still a critical aim in cancer therapy. Though there …

Engineering oncolytic adenoviruses with VSVG‐decorated tumor cell membranes for synergistically enhanced antitumor therapy

LL Huang, W Wang, Z Wang, H Zhang… - Advanced Functional …, 2023 - Wiley Online Library
Oncolytic viruses hold great promise for cancer treatment but their practical applications are
seriously impaired by a series of limitations. Herein, an engineered oncolytic adenovirus …