Mechanism and application of chitosan and its derivatives in promoting permeation in transdermal drug delivery systems: a review

J Ma, Y Wang, R Lu - Pharmaceuticals, 2022 - mdpi.com
The mechanisms and applications of chitosan and its derivatives in transdermal drug
delivery to promote drug permeation were reviewed in this paper. Specifically, we …

Microneedle-mediated transdermal delivery of biopharmaceuticals

HX Nguyen, CN Nguyen - Pharmaceutics, 2023 - mdpi.com
Transdermal delivery provides numerous benefits over conventional routes of
administration. However, this strategy is generally limited to a few molecules with specific …

The progress of fabrication designs of polymeric microneedles and related biomedical applications

X Jiang, W Zhang, R Terry, W Li - BMEMat, 2023 - Wiley Online Library
Microneedles (MNs) have been broadly used for transdermal delivery of a variety of drugs,
ranging from small chemicals to biological macromolecules, due to the properties of …

Microneedle-based technology for cell therapy: current status and future directions

BZ Chen, ZQ Zhao, MA Shahbazi, XD Guo - Nanoscale Horizons, 2022 - pubs.rsc.org
With the growing technological innovations in medical treatments, cell-based therapies hold
great potential as efficient tools against various previously incurable diseases by restoring or …

Photoresponsive polymeric microneedles: An innovative way to monitor and treat diseases

P Singh, B Youden, A Carrier, K Oakes… - Journal of Controlled …, 2023 - Elsevier
Microneedles (MN) technology is an emerging technology for the transdermal delivery of
therapeutics. When combined with photoresponsive (PR) materials, MNs can deliver …

Polymeric microneedles: an emerging paradigm for advanced biomedical applications

D Kulkarni, D Gadade, N Chapaitkar, S Shelke… - Scientia …, 2023 - mdpi.com
Microneedles are gaining popularity as a new paradigm in the area of transdermal drug
delivery for biomedical and healthcare applications. Efficient drug delivery with minimal …

Inverse opal microneedles arrays for fluorescence enhanced screening skin interstitial fluid biomarkers

K Yi, Y Yu, Y Wang, Y Zhao - Nano Today, 2022 - Elsevier
Infectious diseases caused by bacteria have become serious health concerns. Efficient and
sensitive early detections are of pivotal significance in the diagnosis and treatment of …

Insulin-loaded nanoparticles based on acetylated cashew gum/chitosan complexes for oral administration and diabetes treatment

ELV Silva, AC de Jesus Oliveira… - International Journal of …, 2023 - Elsevier
Insulin is one of the most important drugs in the clinical treatment of diabetes. There is
growing interest in oral insulin administration as it mimics the physiological pathway and …

The promising application of hydrogel microneedles in medical application

Y Wu, Z Tang, S Ma, L Du - Journal of Pharmacy and …, 2023 - academic.oup.com
Objectives Hydrogel microneedles are emerging, and promising microneedles mainly
composed of swelling polymers. This review is intended to summarize the preparation …

[HTML][HTML] Microneedles for in situ tissue regeneration

L Long, D Ji, C Hu, L Yang, S Tang, Y Wang - Materials Today Bio, 2023 - Elsevier
Tissue injury is a common clinical problem, which may cause great burden on patients' life. It
is important to develop functional scaffolds to promote tissue repair and regeneration. Due to …