The vasculature of tumours is highly abnormal and dysfunctional. Consequently, immune
effector cells have an impaired ability to penetrate solid tumours and often exhibit …

Anatomical and physiological imaging using CT and MRI are playing a critical role in
patients' diagnosis, disease characterization and treatment planning. CT-and MRI-based …

Background There are concerns over gadolinium deposition from gadolinium‐based
contrast agents (GBCA) administration. Purpose To reduce gadolinium dose in contrast …

This article reviews the application of dynamic contrast-enhanced magnetic resonance
imaging in both clinical studies and early-phase trials of angiogenesis inhibitors. Emphasis …

Preclinical and clinical antiangiogenic approaches, with multiple side effects such as
resistance, have not been proved to be very successful in treating tumor blood vessels …

Quantitative imaging biomarkers show great potential for use in radiotherapy. Quantitative
images based on microscopic tissue properties and tissue function can be used to improve …

Purpose Systems for magnetic resonance (MR-) guided radiotherapy enable daily MR
imaging of cancer patients during treatment, which is of interest for treatment response …

MRI-guided radiotherapy systems have the potential to bring two important concepts in
modern radiotherapy together: adaptive radiotherapy and biological targeting. Based on …

Here we describe the parametric response map (PRM), a voxel-wise approach for image
analysis and quantification of hemodynamic alterations during treatment for 44 patients with …

The purpose of this work was to evaluate the potential of functional imaging with 18F-FDG
PET, 18F-fluoromisonidazole PET, diffusion-weighted MRI, and dynamic contrast-enhanced …