Norovirus

E Robilotti, S Deresinski, BA Pinsky - Clinical microbiology …, 2015 - journals.asm.org
Norovirus, an RNA virus of the family Caliciviridae, is a human enteric pathogen that causes
substantial morbidity across both health care and community settings. Several factors …

Interaction of viral capsid-derived virus-like particles (VLPs) with the innate immune system

MO Mohsen, AC Gomes, M Vogel, MF Bachmann - Vaccines, 2018 - mdpi.com
Virus-like particles (VLPs) derived from viral nucleocapsids are an important class of
nanoparticles. The structure, uniformity, stability, and function of these VLPs have attracted …

Autophagy protein ATG16L1 prevents necroptosis in the intestinal epithelium

YU Matsuzawa-Ishimoto, Y Shono, LE Gomez… - Journal of Experimental …, 2017 - rupress.org
A variant of the autophagy gene ATG16L1 is associated with Crohn's disease, an
inflammatory bowel disease (IBD), and poor survival in allogeneic hematopoietic stem cell …

Norovirus vaccine: priorities for future research and development

S Esposito, N Principi - Frontiers in immunology, 2020 - frontiersin.org
Soon after its identification, norovirus (NoV) has been indicated as one of the most common
causes of outbreaks of acute gastroenteritis (AGE) and sporadic acute diarrhea episodes in …

Noroviruses: Evolutionary dynamics, epidemiology, pathogenesis, and vaccine advances—A comprehensive review

CA Omatola, PP Mshelbwala, MLO Okolo, AB Onoja… - Vaccines, 2024 - mdpi.com
Noroviruses constitute a significant aetiology of sporadic and epidemic gastroenteritis in
human hosts worldwide, especially among young children, the elderly, and …

Viral aptamer screening and aptamer-based biosensors for virus detection: A review

C Hu, S Yang, S Li, X Liu, Y Liu, Z Chen, H Chen… - International Journal of …, 2024 - Elsevier
Virus-induced infectious diseases have a detrimental effect on public health and exert
significant influence on the global economy. Therefore, the rapid and accurate detection of …

[HTML][HTML] Norovirus infection in immunocompromised hosts

KY Green - Clinical Microbiology and Infection, 2014 - Elsevier
Acute gastroenteritis caused by noroviruses often has a duration of 2–0 days and is
characteristically self-limiting. In contrast, chronic infection caused by noroviruses in …

Burden of norovirus in healthcare facilities and strategies for outbreak control

A Kambhampati, M Koopmans, BA Lopman - Journal of Hospital Infection, 2015 - Elsevier
Norovirus is the most frequently occurring cause of community-acquired acute
gastroenteritis in people of all ages. It is also one of the most frequent causes of outbreaks in …

The state of norovirus vaccines

K Debbink, LC Lindesmith… - Clinical Infectious Diseases, 2014 - academic.oup.com
While there is currently no approved norovirus vaccine, recent human clinical efficacy trials
with virus-like particle–based vaccines have shown promise. Several additional norovirus …

Vaccines against gastroenteritis, current progress and challenges

H Seo, Q Duan, W Zhang - Gut Microbes, 2020 - Taylor & Francis
Enteric viral and bacterial infections continue to be a leading cause of mortality and
morbidity in young children in low-income and middle-income countries, the elderly, and …