Cells and extracellular matrices of dentin and pulp: a biological basis for repair and tissue engineering

M Goldberg, AJ Smith - Critical Reviews in Oral Biology & …, 2004 - journals.sagepub.com
Odontoblasts produce most of the extracellular matrix (ECM) components found in dentin
and implicated in dentin mineralization. Major differences in the pulp ECM explain why pulp …

Can interaction of materials with the dentin-pulp complex contribute to dentin regeneration?

JL Ferracane, PR Cooper, AJ Smith - Odontology, 2010 - Springer
Understanding outcomes of the interaction between a dental material and tooth tissue is
important in terms not only of biocompatibilty but also of the potential for the material to …

Effects of alginate hydrogels and TGF-β1 on human dental pulp repair in vitro

K Dobie, G Smith, AJ Sloan, AJ Smith - Connective tissue research, 2002 - Taylor & Francis
The objective of this study was to investigate the use of alginate hydrogels to present either
exogenous or endogenous transforming growth factor (TGF)-g 1 to the dentin-pulp complex …

Effects of VEGF and FGF2 on the revascularization of severed human dental pulps

EM Mullane, Z Dong, CM Sedgley… - Journal of dental …, 2008 - journals.sagepub.com
The long-term outcome of replanted avulsed permanent teeth is frequently compromised by
lack of revascularization, resulting in pulp necrosis. The purpose of this study was to …

Animal models for stem cell-based pulp regeneration: foundation for human clinical applications

M Nakashima, K Iohara, MC Bottino… - … Engineering Part B …, 2019 - liebertpub.com
Rapid progress has been made in the last decade related to stem cell-mediated pulp–dentin
regeneration, from characterization of dental pulp stem cells (DPSCs) to the first-ever …

In vitro, ex vivo, and in vivo models for dental pulp regeneration

SS Piglionico, C Pons, O Romieu, F Cuisinier… - Journal of Materials …, 2023 - Springer
Based on the concept of tissue engineering (Cells—Scaffold—Bioactive molecules),
regenerative endodontics appeared as a new notion for dental endodontic treatment. Its …

Tooth slice/scaffold model of dental pulp tissue engineering

VT Sakai, MM Cordeiro, Z Dong… - Advances in dental …, 2011 - journals.sagepub.com
Multipotency is a defining characteristic of post-natal stem cells. The human dental pulp
contains a small subpopulation of stem cells that exhibit multipotency, as demonstrated by …

Tooth slice organ culture and established cell line culture models for cytotoxicity assessment of dental materials

TY Saw, T Cao, AUJ Yap, MML Ng - Toxicology in vitro, 2005 - Elsevier
The aim was to compare the use of different cell–material contact test methods with two
different biological systems (cell line and tooth slice cultures) for cytotoxicity assessment of …

Tooth slice–based models for the study of human dental pulp angiogenesis

SB Gonçalves, Z Dong, CM Bramante, GR Holland… - Journal of …, 2007 - Elsevier
Treatment of avulsed young permanent teeth aims to revascularize the dental pulp. The
study of therapeutic strategies for avulsed teeth has been hindered by the scarcity of …

[HTML][HTML] A compilation of study models for dental pulp regeneration

E Ohlsson, KM Galler, M Widbiller - International Journal of Molecular …, 2022 - mdpi.com
Efforts to heal damaged pulp tissue through tissue engineering have produced positive
results in pilot trials. However, the differentiation between real regeneration and mere repair …