Antifungal prophylaxis in adult patients with acute myeloid leukaemia treated with novel targeted therapies: a systematic review and expert consensus …

J Stemler, N de Jonge, N Skoetz, J Sinkó… - The Lancet …, 2022 - thelancet.com
On the basis of improved overall survival, treatment guidelines strongly recommend
antifungal prophylaxis during remission induction chemotherapy for patients with acute …

Approach to the older patient with acute myeloid leukemia

M Zimmer, T Kadia - Current oncology reports, 2023 - Springer
Abstract Purpose of Review This study aims to review the challenges of treating AML in
older patients, the spectrum of genomic aberrancies in this cohort, and discuss treatment …

Characterisation of infections in patients with acute myeloid leukaemia receiving venetoclax and a hypomethylating agent

S On, CG Rath, M Lan, B Wu, KM Lau… - British Journal of …, 2022 - Wiley Online Library
We investigated the incidence of invasive fungal infections (IFIs) and other infectious
complications in patients receiving venetoclax and hypomethylating agent therapy for acute …

Incidence of invasive fungal infections in patients with previously untreated acute myeloid leukemia receiving venetoclax and azacitidine

A Zhang, T Johnson, D Abbott… - Open Forum …, 2022 - academic.oup.com
Background Acute myeloid leukemia (AML) is associated with poor prognosis, particularly in
elderly patients with comorbidities. Combining azacitidine (AZA) with BCL-2 inhibitor …

High-risk neutropenic fever and invasive fungal diseases in patients with hematological malignancies

G Mori, S Diotallevi, F Farina, R Lolatto, L Galli… - Microorganisms, 2024 - mdpi.com
Invasive fungal diseases (IFDs) still represent a relevant cause of mortality in patients
affected by hematological malignancies, especially acute myeloid leukaemia (AML) and …

Fungal Intracranial Infections (Central Nervous System‐Invasive Fungal Disease) in Patients With Haematological Disorders—A Single‐Centre Retrospective Study

S Chattopadhyay, LJ Sumanth, HA Vanjare… - Mycoses, 2024 - Wiley Online Library
Background Invasive fungal disease (IFD) is a sinister complication encountered in patients
with haematological disorders. When occurring in the central nervous system (CNS), IFDs …

The Development of a Human-Relevant Pre-Clinical Mouse Model of Disseminated Cerebral Aspergillosis and Defining the Subsequent Neuroimmune Response

BN Sullivan - 2022 - search.proquest.com
Exposure of immunosuppressed individuals to the opportunistic fungal pathogen Aspergillus
(A.) fumigatus may result in invasive pulmonary aspergillosis (IPA), which could lead to the …