Antiretroviral treatment of HIV-1 prevents transmission of HIV-1: where do we go from here?
Antiretroviral drugs that inhibit viral replication were expected to reduce transmission of HIV
by lowering the concentration of HIV in the genital tract. In 11 of 13 observational studies …
by lowering the concentration of HIV in the genital tract. In 11 of 13 observational studies …
Antiretroviral drug resistance testing in adults with HIV infection: implications for clinical management
MS Hirsch, B Conway, TD Richard, VA Johnson… - Jama, 1998 - jamanetwork.com
Objectives.—To review current knowledge of the biology and clinical implications of human
immunodeficiency virus (HIV) resistance to antiretroviral drugs, describe assays for …
immunodeficiency virus (HIV) resistance to antiretroviral drugs, describe assays for …
Antiretroviral-drug resistance among patients recently infected with HIV
Background Among persons in North America who are newly infected with the human
immunodeficiency virus (HIV), the prevalence of transmitted resistance to antiretroviral drugs …
immunodeficiency virus (HIV), the prevalence of transmitted resistance to antiretroviral drugs …
Public health implications of antiretroviral therapy and HIV drug resistance
MA Wainberg, G Friedland - Jama, 1998 - jamanetwork.com
Widespread use of antiretroviral agents and increasing occurrence of human
immunodeficiency virus (HIV) strains resistant to these drugs have given rise to a number of …
immunodeficiency virus (HIV) strains resistant to these drugs have given rise to a number of …
Viral dynamics of acute HIV-1 infection
Viral dynamics were intensively investigated in eight patients with acute HIV infection to
define the earliest rates of change in plasma HIV RNA before and after the start of …
define the earliest rates of change in plasma HIV RNA before and after the start of …
Time trends in primary HIV-1 drug resistance among recently infected persons
RM Grant, FM Hecht, M Warmerdam, L Liu, T Liegler… - Jama, 2002 - jamanetwork.com
ContextTransmission of multiclass drug-resistant human immunodeficiency virus type 1 (HIV-
1) may increase with wider use of antiretroviral therapy. ObjectiveTo determine trends in …
1) may increase with wider use of antiretroviral therapy. ObjectiveTo determine trends in …
HIV-1 drug resistance in newly infected individuals
D Boden, A Hurley, L Zhang, Y Cao, Y Guo, E Jones… - Jama, 1999 - jamanetwork.com
ContextThere is concern that the widespread use of antiretroviral drugs to treat human
immunodeficiency virus 1 (HIV-1) infection may result in the increased transmission of drug …
immunodeficiency virus 1 (HIV-1) infection may result in the increased transmission of drug …
Sexual transmission of an HIV-1 variant resistant to multiple reverse-transcriptase and protease inhibitors
FM Hecht, RM Grant, CJ Petropoulos… - … England Journal of …, 1998 - Mass Medical Soc
Combination treatments with agents that inhibit protease and reverse transcriptase of human
immunodeficiency virus type 1 (HIV-1) decrease mortality and slow disease progression. 1 …
immunodeficiency virus type 1 (HIV-1) decrease mortality and slow disease progression. 1 …
Treatment to prevent transmission of HIV-1
MS Cohen, CL Gay - Clinical infectious diseases, 2010 - academic.oup.com
Antiretroviral therapy (ART) has the potential to prevent human immunodeficiency virus
(HIV) transmission by reducing the concentration of HIV in blood and genital secretions …
(HIV) transmission by reducing the concentration of HIV in blood and genital secretions …
Transmission of antiretroviral-drug-resistant HIV-1 variants
S Yerly, L Kaiser, E Race, JP Bru, F Clavel, L Perrin - The Lancet, 1999 - thelancet.com
Background Resistance of HIV-1 to antiretroviral drugs is the main cause of antiretroviral-
treatment failure. We assessed the transmission of drug-resistant variants among individuals …
treatment failure. We assessed the transmission of drug-resistant variants among individuals …