Liquid biopsy at the frontier of detection, prognosis and progression monitoring in colorectal cancer

H Zhou, L Zhu, J Song, G Wang, P Li, W Li, P Luo… - Molecular cancer, 2022 - Springer
Colorectal cancer (CRC) is one of the most common cancers worldwide and a leading
cause of carcinogenic death. To date, surgical resection is regarded as the gold standard by …

A review of circulating tumour cell enrichment technologies

AJ Rushton, G Nteliopoulos, JA Shaw, RC Coombes - Cancers, 2021 - mdpi.com
Simple Summary Circulating tumour cells (CTCs) are cancer cells shed into the bloodstream
from tumours and their analysis can provide important insights into cancer detection and …

Nanotechnology strategies to advance outcomes in clinical cancer care

CM Hartshorn, MS Bradbury, GM Lanza, AE Nel… - ACS …, 2018 - ACS Publications
Ongoing research into the application of nanotechnology for cancer treatment and diagnosis
has demonstrated its advantages within contemporary oncology as well as its intrinsic …

Targeted therapies for renal cell carcinoma

EM Posadas, S Limvorasak, RA Figlin - Nature Reviews Nephrology, 2017 - nature.com
The management of patients with metastatic renal cell carcinoma (RCC) has changed
dramatically over the past few years. Nephrectomy remains an important intervention for …

Safety and efficacy of BIND-014, a docetaxel nanoparticle targeting prostate-specific membrane antigen for patients with metastatic castration-resistant prostate cancer …

KA Autio, R Dreicer, J Anderson, JA Garcia… - JAMA …, 2018 - jamanetwork.com
Importance Preferential delivery of docetaxel to tumors by prostate-specific membrane
antigen (PSMA)–targeted nanoparticles is clinically effective, and the selective reduction of …

Tumour heterogeneity: the key advantages of single-cell analysis

M Tellez-Gabriel, B Ory, F Lamoureux… - International journal of …, 2016 - mdpi.com
Tumour heterogeneity refers to the fact that different tumour cells can show distinct
morphological and phenotypic profiles, including cellular morphology, gene expression …

Nanostructured substrates for detection and characterization of circulating rare cells: from materials research to clinical applications

J Dong, JF Chen, M Smalley, M Zhao, Z Ke… - Advanced …, 2020 - Wiley Online Library
Circulating rare cells in the blood are of great significance for both materials research and
clinical applications. For example, circulating tumor cells (CTCs) have been demonstrated …

Materials and microfluidics: enabling the efficient isolation and analysis of circulating tumour cells

JM Jackson, MA Witek, JW Kamande… - Chemical Society …, 2017 - pubs.rsc.org
We present a critical review of microfluidic technologies and material effects on the analyses
of circulating tumour cells (CTCs) selected from the peripheral blood of cancer patients …

[HTML][HTML] Circulating tumor cells: moving biological insights into detection

L Chen, AM Bode, Z Dong - Theranostics, 2017 - ncbi.nlm.nih.gov
Circulating tumor cells (CTCs) have shown promising potential as liquid biopsies that
facilitate early detection, prognosis, therapeutic target selection and monitoring treatment …

Concise review: prostate cancer stem cells: current understanding

S Skvortsov, II Skvortsova, DG Tang, A Dubrovska - Stem Cells, 2018 - academic.oup.com
Prostate cancer (PCa) is heterogeneous, harboring phenotypically diverse cancer cell types.
PCa cell heterogeneity is caused by genomic instability that leads to the clonal competition …