Allergen immunotherapy is effective in patients with IgE-dependent allergic rhinitis and
asthma. When immunotherapy is given continuously for 3 years, there is persistent clinical …

Modern health care requires a proactive and individualized response to diseases,
combining precision diagnosis and personalized treatment. Accordingly, the approach to …

Regulatory T cells prevent the emergence of autoantibodies and excessive IgE, but the
precise mechanisms are unclear. Here, we show that BCL6-expressing Tregs, known as …

CD4+ T helper (TH) cells and regulatory T (Treg) cells that respond to common allergens
play an important role in driving and dampening airway inflammation in patients with …

Allergic diseases are characterized by overactive type 2 immune responses to allergens and
immunoglobulin E (IgE)‐mediated hypersensitivity. Emerging evidence suggests that …

Allergen‐specific immunotherapy (AIT) is an allergen‐specific form of treatment for patients
suffering from immunoglobulin E (IgE)‐associated allergy; the most common and important …

Objective The aim of this review is to provide an overview of the current knowledge on the
mechanisms of allergen immunotherapy based on the recent publications and clinical trials …

Long-term efficacy that occurs with allergen immunotherapy of proven value is associated
with decreases in IgE-dependent activation of mast cells and tissue eosinophilia. This …

Hymenoptera stings may cause both local and systemic allergic reactions and even life
threatening anaphylaxis. Along with pharmaceutical drugs and foods, hymenoptera venom …

T follicular helper (Tfh) cells are a specialized subset of CD4+ T cells that collaborate with B
cells to promote and regulate humoral responses. Unlike other CD4+ effector lineages, Tfh …