Significant progress has been made in understanding the neurobiological mechanisms
through which exercise protects and restores the brain. In this feature review, we integrate …

Among age-related diseases, cardiovascular and cerebrovascular diseases are major
causes of death. Vascular dysfunction is a key characteristic of these diseases wherein age …

We present a review of the characterization of healthy brain aging using MRI with an
emphasis on morphology, lesions, and quantitative MR parameters. A scope review found …

New representations of tree-structured data objects, using ideas from topological data
analysis, enable improved statistical analyses of a population of brain artery trees. A number …

As the global population faces a progressive shift towards a higher median age,
understanding the mechanisms underlying healthy brain ageing has become of paramount …

Cardiovascular disease is a deadly global health crisis that carries a substantial financial
burden. Innovative treatment and management of cardiovascular disease straddles …

Biological brain age predicted using machine learning models based on high‐resolution
imaging data has been suggested as a potential biomarker for neurological and …

Purpose To develop a quantitative intracranial artery measurement technique to extract
comprehensive artery features from time‐of‐flight MR angiography (MRA). Methods By …

BACKGROUND AND PURPOSE: Prior studies suggest that aerobic exercise may reduce
both the brain atrophy and the decline in fractional anisotropy observed with advancing age …

Aging of the vasculature, which is integral to the functioning of literally all human organs,
serves as a fundamental physiological basis for age-related alterations as well as a shared …