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[HTML][HTML] Evaluation of the anti-diabetic activity of some common herbs and spices: providing new insights with inverse virtual screening
Culinary herbs and spices are widely used as a traditional medicine in the treatment of
diabetes and its complications, and there are several scientific studies in the literature …
diabetes and its complications, and there are several scientific studies in the literature …
[HTML][HTML] The potential antidiabetic properties of green and purple tea [Camellia sinensis (L.) O Kuntze], purple tea ellagitannins, and urolithins
Abstract Ethnopharmacological relevance Tea (Camellia sinensis) has been consumed for
centuries as traditional medicine for various diseases, including diabetes. The mechanism of …
centuries as traditional medicine for various diseases, including diabetes. The mechanism of …
Fishing the Targets of Bioactive Compounds from Psidium guajava L. Leaves in the Context of Diabetes
Psidium guajava L.(guava) leaves have demonstrated their in vitro and in vivo effect against
diabetes mellitus (DM). However, there is a lack of literature concerning the effect of the …
diabetes mellitus (DM). However, there is a lack of literature concerning the effect of the …
[HTML][HTML] Computational study of Asian propolis compounds as potential anti-type 2 diabetes mellitus agents by using inverse virtual screening with the DIA-DB web …
Propolis contains a wide range of pharmacological activities because of their various
bioactive compounds. The beneficial effect of propolis is interesting for treating type-2 …
bioactive compounds. The beneficial effect of propolis is interesting for treating type-2 …
[HTML][HTML] Exploring African medicinal plants for potential anti-diabetic compounds with the DIA-DB inverse virtual screening web server
Medicinal plants containing complex mixtures of several compounds with various potential
beneficial biological effects are attractive treatment interventions for a complex multi-faceted …
beneficial biological effects are attractive treatment interventions for a complex multi-faceted …
Design, synthesis and in combo antidiabetic bioevaluation of multitarget phenylpropanoic acids
We have synthesized a small series of five 3-[4-arylmethoxy) phenyl] propanoic acids
employing an easy and short synthetic pathway. The compounds were tested in vitro against …
employing an easy and short synthetic pathway. The compounds were tested in vitro against …
DIA-DB: A database and web server for the prediction of diabetes drugs
The DIA-DB is a web server for the prediction of diabetes drugs that uses two different and
complementary approaches:(a) comparison by shape similarity against a curated database …
complementary approaches:(a) comparison by shape similarity against a curated database …
Valorisation of stachysetin from cultivated Stachys iva Griseb. as anti-diabetic agent: a multi-spectroscopic and molecular docking approach
A Pritsas, EM Tomou, E Tsitsigianni… - Journal of …, 2021 - Taylor & Francis
Stachys species are considered as important medicinal plants with numerous health benefit
effects. In continuation of our research on the Greek Stachys species, the chemical profile of …
effects. In continuation of our research on the Greek Stachys species, the chemical profile of …
Gaining deeper insights into 2, 5-disubstituted furan derivatives as potent α-glucosidase inhibitors and discovery of putative targets associated with diabetes diseases …
In the quest to treat diabetes, nowadays, the enthusiasm for the development of novel drugs
with strong α-glucosidase inhibitory action and negligible or no adverse effects has received …
with strong α-glucosidase inhibitory action and negligible or no adverse effects has received …
[HTML][HTML] Design, synthesis, in vitro, in vivo and in silico pharmacological characterization of antidiabetic N-Boc-L-tyrosine-based compounds
In this study, we synthesized five N-Boc-L-tyrosine-based analogues to glitazars. The in vitro
effects of compounds 1–5 on protein tyrosine phosphatase 1B (PTP-1B), peroxisome …
effects of compounds 1–5 on protein tyrosine phosphatase 1B (PTP-1B), peroxisome …