[HTML][HTML] Evaluation of the anti-diabetic activity of some common herbs and spices: providing new insights with inverse virtual screening

ASP Pereira, AJ Banegas-Luna, J Peña-García… - Molecules, 2019 - mdpi.com
Culinary herbs and spices are widely used as a traditional medicine in the treatment of
diabetes and its complications, and there are several scientific studies in the literature …

[HTML][HTML] The potential antidiabetic properties of green and purple tea [Camellia sinensis (L.) O Kuntze], purple tea ellagitannins, and urolithins

M Tolmie, MJ Bester, JC Serem, M Nell… - Journal of …, 2023 - Elsevier
Abstract Ethnopharmacological relevance Tea (Camellia sinensis) has been consumed for
centuries as traditional medicine for various diseases, including diabetes. The mechanism of …

Fishing the Targets of Bioactive Compounds from Psidium guajava L. Leaves in the Context of Diabetes

E Díaz-de-Cerio, F Girón, A Pérez-Garrido… - International Journal of …, 2023 - mdpi.com
Psidium guajava L.(guava) leaves have demonstrated their in vitro and in vivo effect against
diabetes mellitus (DM). However, there is a lack of literature concerning the effect of the …

[HTML][HTML] Computational study of Asian propolis compounds as potential anti-type 2 diabetes mellitus agents by using inverse virtual screening with the DIA-DB web …

PH Syaifie, AH Harisna, MAF Nasution, AG Arda… - Molecules, 2022 - mdpi.com
Propolis contains a wide range of pharmacological activities because of their various
bioactive compounds. The beneficial effect of propolis is interesting for treating type-2 …

[HTML][HTML] Exploring African medicinal plants for potential anti-diabetic compounds with the DIA-DB inverse virtual screening web server

ASP Pereira, H den Haan, J Peña-García, MM Moreno… - Molecules, 2019 - mdpi.com
Medicinal plants containing complex mixtures of several compounds with various potential
beneficial biological effects are attractive treatment interventions for a complex multi-faceted …

Design, synthesis and in combo antidiabetic bioevaluation of multitarget phenylpropanoic acids

B Colín-Lozano, S Estrada-Soto, F Chávez-Silva… - Molecules, 2018 - mdpi.com
We have synthesized a small series of five 3-[4-arylmethoxy) phenyl] propanoic acids
employing an easy and short synthetic pathway. The compounds were tested in vitro against …

DIA-DB: A database and web server for the prediction of diabetes drugs

H Pérez-Sánchez, H den-Haan… - Journal of Chemical …, 2020 - ACS Publications
The DIA-DB is a web server for the prediction of diabetes drugs that uses two different and
complementary approaches:(a) comparison by shape similarity against a curated database …

Valorisation of stachysetin from cultivated Stachys iva Griseb. as anti-diabetic agent: a multi-spectroscopic and molecular docking approach

A Pritsas, EM Tomou, E Tsitsigianni… - Journal of …, 2021 - Taylor & Francis
Stachys species are considered as important medicinal plants with numerous health benefit
effects. In continuation of our research on the Greek Stachys species, the chemical profile of …

Gaining deeper insights into 2, 5-disubstituted furan derivatives as potent α-glucosidase inhibitors and discovery of putative targets associated with diabetes diseases …

WE Prasetyo, T Kusumaningsih, FR Wibowo - Structural Chemistry, 2023 - Springer
In the quest to treat diabetes, nowadays, the enthusiasm for the development of novel drugs
with strong α-glucosidase inhibitory action and negligible or no adverse effects has received …

[HTML][HTML] Design, synthesis, in vitro, in vivo and in silico pharmacological characterization of antidiabetic N-Boc-L-tyrosine-based compounds

MÁ Herrera-Rueda, H Tlahuext, P Paoli… - Biomedicine & …, 2018 - Elsevier
In this study, we synthesized five N-Boc-L-tyrosine-based analogues to glitazars. The in vitro
effects of compounds 1–5 on protein tyrosine phosphatase 1B (PTP-1B), peroxisome …