Microfluidic‐based approaches in targeted cell/particle separation based on physical properties: fundamentals and applications

R Nasiri, A Shamloo, S Ahadian, L Amirifar, J Akbari… - Small, 2020 - Wiley Online Library
Cell separation is a key step in many biomedical research areas including biotechnology,
cancer research, regenerative medicine, and drug discovery. While conventional cell sorting …

Emerging technologies and commercial products in exosome-based cancer diagnosis and prognosis

M Mohammadi, H Zargartalebi, R Salahandish… - Biosensors and …, 2021 - Elsevier
Academic and industrial groups worldwide have reported technological advances in
exosome-based cancer diagnosis and prognosis. However, the potential translation of these …

Magnetic particle targeting for diagnosis and therapy of lung cancers

M Saadat, MKD Manshadi, M Mohammadi… - Journal of Controlled …, 2020 - Elsevier
Over the past decade, the growing interest in targeted lung cancer therapy has guided
researchers toward the cutting edge of controlled drug delivery, particularly magnetic …

[HTML][HTML] A micropillar array-based microfluidic chip for label-free separation of circulating tumor cells: The best micropillar geometry?

M Rahmanian, OS Hematabad, E Askari… - Journal of Advanced …, 2023 - Elsevier
Introduction The information derived from the number and characteristics of circulating tumor
cells (CTCs), is crucial to ensure appropriate cancer treatment monitoring. Currently, diverse …

The detection of the captured circulating tumor cells on the core‐shell nanofibrous membrane using hyaluronic acid‐functionalized graphene quantum dots

S Asghari, M Mahmoudifard - Journal of Biomedical Materials …, 2023 - Wiley Online Library
In recent years, cancerous cases have increased remarkably worldwide, and metastasis is
the leading cause of death. Therefore, research on the early detection of cancer and …

Microfluidic devices for the isolation and label-free identification of circulating tumor cells

M Anwar, NM Reis, C Zhang, A Khan… - Chemical Engineering …, 2024 - Elsevier
The isolation and identification of circulating tumor cells (CTCs) from blood samples
provides a great opportunity for prevention of metastatic cancer and assist early diagnosis …

Circulating tumor cell-derived pre-clinical models for personalized medicine

M Tellez-Gabriel, D Cochonneau, M Cadé, C Jubelin… - Cancers, 2018 - mdpi.com
The main cause of death from cancer is associated with the development of metastases,
resulting from the inability of current therapies to cure patients at metastatic stages …

Magnetically-activated, nanostructured cellulose for efficient capture of circulating tumor cells from the blood sample of head and neck cancer patients

RS Hazra, N Kale, C Boyle, KB Molina, A D'Souza… - Carbohydrate …, 2024 - Elsevier
In this report, the relative efficiency of cellulose nanocrystals (CNCs) and nanofibers (CNFs)
to capture circulating tumor cells (CTCs) from the blood sample of head and neck cancer …

Efficient separation of tumor cells from untreated whole blood using a novel multistage hydrodynamic focusing microfluidics

R Gao, L Cheng, S Wang, X Bi, X Wang, R Wang… - Talanta, 2020 - Elsevier
Significant progress on circulating tumor cells (CTCs) has profound impact for noninvasive
tumor profiling including early diagnosis, treatment monitoring, and metastasis recognition …

Hybrid negative enrichment of circulating tumor cells from whole blood in a 3D-printed monolithic device

CH Chu, R Liu, T Ozkaya-Ahmadov, M Boya… - Lab on a Chip, 2019 - pubs.rsc.org
Isolation and analysis of circulating tumor cells (CTCs) from blood samples present exciting
opportunities for basic cancer research and personalized treatment of the disease. While …