Mucosal immune response in biology, disease prevention and treatment

X Zhou, Y Wu, Z Zhu, C Lu, C Zhang, L Zeng… - … and Targeted Therapy, 2025 - nature.com
The mucosal immune system, as the most extensive peripheral immune network, serves as
the frontline defense against a myriad of microbial and dietary antigens. It is crucial in …

Vaccine responses in patients with liver cirrhosis: from the immune system to the gut microbiota

C Airola, S Andaloro, A Gasbarrini, FR Ponziani - Vaccines, 2024 - mdpi.com
Vaccines prevent a significant number of deaths annually. However, certain populations do
not respond adequately to vaccination due to impaired immune systems. Cirrhosis, a …

The development of a human Brucella mucosal vaccine: What should be considered?

T Tian, Y Zhu, J Shi, K Shang, Z Yin, H Shi, Y He… - Life Sciences, 2024 - Elsevier
Brucellosis is a chronic infectious disease that is zoonotic in nature. Brucella can infect
humans through interactions with livestock, primarily via the digestive tract, respiratory tract …

Recent development of oral vaccines

Y Liu, DMK Lam, M Luan… - Experimental and …, 2024 - spandidos-publications.com
Oral immunization can elicit an effective immune response and immune tolerance to specific
antigens. When compared with the traditional injection route, delivering antigens via the …

[HTML][HTML] Per Os to Protection–targeting the oral route to enhance immune-mediated protection from disease of the human newborn

V Verhasselt, A Marchant, TR Kollmann - Journal of Molecular Biology, 2024 - Elsevier
Insight into the mechanisms that guide the host immune response towards either
immunogenicity or tolerance is crucial for the success of many biomedical interventions …

Alginate functionalized chitosan nanoparticles using multilayer co-axial electro-spraying for ovalbumin controlled release via oral delivery

LNH Cao, TV Nguyen, NQ Nguyen, TBT Nguyen… - Journal of Drug Delivery …, 2024 - Elsevier
The current oral vaccine delivery presents numerous challenges due to physiological
barriers in the gastrointestinal tract including antigen degradation by enzymes and gastric …

The Current Status and Development Forecasts of Vaccines for Aquaculture and its Effects on Bacterial and Viral Diseases

EM Mkulo, B Wang, K Amoah, Y Huang, C Jia… - Microbial …, 2024 - Elsevier
The aquaculture sector predicts protein-rich meals by 2040 and has experienced significant
economic shifts since 2000. However, challenges emanating from disease control …

[HTML][HTML] Immature B cell homing shapes human lymphoid tissue structure and function

J Spencer, C Dionisi - The Journal of Experimental Medicine, 2024 - pmc.ncbi.nlm.nih.gov
Shortly after the emergence of newly formed human B cells from bone marrow as transitional
cells, they diverge along two developmental pathways that can be distinguished by the level …

[HTML][HTML] Recent Advances in Oral Vaccines for Animals

K Zhong, X Chen, J Zhang, X Jiang, J Zhang… - Veterinary …, 2024 - mdpi.com
Simple Summary Oral vaccines provide a gentle and convenient way to prevent infectious
diseases in animals while inducing robust mucosal immunity that is particularly effective …

Current Status and Opportunities of Immunological Research on Percid Fishes

T Gebauer, R Gebauer, V Stejskal… - Reviews in Fisheries …, 2024 - Taylor & Francis
The diversification of modern aquaculture systems with high-value finfish species, including
Percidae, is hampered by various diseases or even epidemics caused by a wide range of …