[HTML][HTML] Pharmaceutical amorphous solid dispersion: A review of manufacturing strategies
Amorphous solid dispersions (ASDs) are popular for enhancing the solubility and
bioavailability of poorly water-soluble drugs. Various approaches have been employed to …
bioavailability of poorly water-soluble drugs. Various approaches have been employed to …
Artificial intelligence in drug toxicity prediction: recent advances, challenges, and future perspectives
Toxicity prediction is a critical step in the drug discovery process that helps identify and
prioritize compounds with the greatest potential for safe and effective use in humans, while …
prioritize compounds with the greatest potential for safe and effective use in humans, while …
DrugCentral 2021 supports drug discovery and repositioning
DrugCentral is a public resource (http://drugcentral. org) that serves the scientific community
by providing up-to-date drug information, as described in previous papers. The current …
by providing up-to-date drug information, as described in previous papers. The current …
BDDCS, the Rule of 5 and drugability
The Rule of 5 methodology appears to be as useful today in defining drugability as when it
was proposed, but recognizing that the database that we used includes only drugs that …
was proposed, but recognizing that the database that we used includes only drugs that …
Effect of P-glycoprotein (P-gp) inducers on exposure of P-gp substrates: review of clinical drug–drug interaction studies
Understanding transporter-mediated drug–drug interactions (DDIs) for investigational
agents is important during drug development to assess DDI liability, its clinical relevance …
agents is important during drug development to assess DDI liability, its clinical relevance …
Praziquantel for schistosomiasis: single-drug metabolism revisited, mode of action, and resistance
Schistosomiasis, a major neglected tropical disease, affects more than 250 million people
worldwide. Treatment of schistosomiasis has relied on the anthelmintic drug praziquantel …
worldwide. Treatment of schistosomiasis has relied on the anthelmintic drug praziquantel …
Cannabinoid formulations and delivery systems: Current and future options to treat pain
B Stella, F Baratta, C Della Pepa, S Arpicco, D Gastaldi… - Drugs, 2021 - Springer
The field of Cannabis sativa L. research for medical purposes has been rapidly advancing in
recent decades and a growing body of evidence suggests that phytocannabinoids are …
recent decades and a growing body of evidence suggests that phytocannabinoids are …
[HTML][HTML] The influence of the gut microbiota on the bioavailability of oral drugs
X Zhang, Y Han, W Huang, M **, Z Gao - Acta Pharmaceutica Sinica B, 2021 - Elsevier
Due to its safety, convenience, low cost and good compliance, oral administration attracts
lots of attention. However, the efficacy of many oral drugs is limited to their unsatisfactory …
lots of attention. However, the efficacy of many oral drugs is limited to their unsatisfactory …
Amorphous solid dispersions: Rational selection of a manufacturing process
Amorphous products and particularly amorphous solid dispersions are currently one of the
most exciting areas in the pharmaceutical field. This approach presents huge potential and …
most exciting areas in the pharmaceutical field. This approach presents huge potential and …
Advances and future perspectives in epithelial drug delivery
Epithelial surfaces protect exposed tissues in the body against intrusion of foreign materials,
including xenobiotics, pollen and microbiota. The relative permeability of the various …
including xenobiotics, pollen and microbiota. The relative permeability of the various …