[HTML][HTML] Exosomes in angiogenesis and anti-angiogenic therapy in cancers

W Olejarz, G Kubiak-Tomaszewska… - International Journal of …, 2020 - mdpi.com
Angiogenesis is the process through which new blood vessels are formed from pre-existing
ones. Exosomes are involved in angiogenesis in cancer progression by transporting …

Lipid based nanoparticles as a novel treatment modality for hepatocellular carcinoma: a comprehensive review on targeting and recent advances

K Mahmoud, S Swidan, M El-Nabarawi… - Journal of …, 2022 - Springer
Liver cancer is considered one of the deadliest diseases with one of the highest disease
burdens worldwide. Among the different types of liver cancer, hepatocellular carcinoma is …

[HTML][HTML] Survival strategies: How tumor hypoxia microenvironment orchestrates angiogenesis

M Yang, Y Mu, X Yu, D Gao, W Zhang, Y Li, J Liu… - Biomedicine & …, 2024 - Elsevier
During tumor development, the tumor itself must continuously generate new blood vessels to
meet their growth needs while also allowing for tumor invasion and metastasis. One of the …

lncRNA miR4458HG modulates hepatocellular carcinoma progression by activating m6A-dependent glycolysis and promoting the polarization of tumor-associated …

Y Ye, M Wang, G Wang, Z Mai, B Zhou, Y Han… - Cellular and Molecular …, 2023 - Springer
Long non-coding RNAs (lncRNAs) play significant roles in different biological functions of
cancers. However, their function in the metabolism of glucose in patients with human …

Multimodality annotated hepatocellular carcinoma data set including pre-and post-TACE with imaging segmentation

AW Moawad, A Morshid, AM Khalaf, MM Elmohr… - Scientific data, 2023 - nature.com
Hepatocellular carcinoma (HCC) is the most common primary liver neoplasm, and its
incidence has doubled over the past two decades owing to increasing risk factors. Despite …

Copper homeostasis and cuproptosis in health and disease

Y Yang, J Wu, L Wang, G Ji, Y Dang - MedComm, 2024 - Wiley Online Library
Copper is a vital trace element in human physiology, essential for the synthesis of numerous
crucial metabolic enzymes and facilitation of various biological processes. Regulation of …

The important role of miR-1-3p in cancers

S Dai, F Li, S Xu, J Hu, L Gao - Journal of Translational Medicine, 2023 - Springer
Cancer is a malignant tumor that seriously threatens human life and health. At present, the
main treatment methods include surgical resection, chemotherapy, radiotherapy, and …

Targeting the SphK1/S1P/PFKFB3 axis suppresses hepatocellular carcinoma progression by disrupting glycolytic energy supply that drives tumor angiogenesis

XT Liu, Y Huang, D Liu, YC Jiang, M Zhao… - Journal of translational …, 2024 - Springer
Background Hepatocellular carcinoma (HCC) remains a leading life-threatening health
challenge worldwide, with pressing needs for novel therapeutic strategies. Sphingosine …

Exploring a novel thiazole derivatives hybrid with fluorinated-indenoquinoxaline as dual inhibitors targeting VEGFR2/AKT and apoptosis inducers against …

MS Abusaif, A Ragab, EA Fayed, YA Ammar… - Bioorganic …, 2025 - Elsevier
Hepatocellular carcinoma (HCC) ranks as the third most prevalent reason for cancer-related
death on a global scale. Tyrosine kinase inhibitors (TKIs) continue to be the primary …

Cogent role of flavonoids as key orchestrators of chemoprevention of hepatocellular carcinoma: A review

J Baby, AR Devan, AR Kumar… - Journal of Food …, 2021 - Wiley Online Library
Chemopreventive approaches with food‐derived phytochemicals are progressively rising as
a significant aspect of tumor management and control. Herein, we have showcased the …