The global burden caused by cardiovascular disease is substantial, with heart disease
representing the most common cause of death around the world. There remains a need to …

In a normal human life span, the heart beats about 2–3 billion times. Under diseased
conditions, a heart may lose its normal rhythm and degenerate suddenly into much faster …

The clinical application of high-voltage defibrillation to eliminate spiral waves in the cardiac
possesses profound adverse effects. There is a demand for alternative approaches with …

Controlling the complex spatio-temporal dynamics underlying life-threatening cardiac
arrhythmias such as fibrillation is extremely difficult, because of the nonlinear interaction of …

The beating of the heart is a synchronized contraction of muscle cells (myocytes) that is
triggered by a periodic sequence of electrical waves (action potentials) originating in the …

Background—Electrically based therapies for terminating atrial fibrillation (AF) currently fall
into 2 categories: antitachycardia pacing and cardioversion. Antitachycardia pacing uses …

A normal heartbeat is orchestrated by the stable propagation of an excitation wave that
produces an orderly contraction. In contrast, wave turbulence in the ventricles, clinically …

Complex spatiotemporal non-linearity as observed during cardiac arrhythmia strongly
correlates with vortex-like excitation wavelengths and tissue characteristics. Therefore, the …

Current treatments of cardiac arrhythmias like ventricular fibrillation involve the application of
a high-energy electric shock, that induces significant electrical currents in the myocardium …

The dynamics of many cardiac arrhythmias, as well as the nature of transitions between
different heart rhythms, have long been considered evidence of nonlinear phenomena …