G6PD was discovered and biochemically characterized in 1932 by Otto Warburg and Walter
Christian 1 in yeast and in red cells as an enzyme with a redox function. It was one of the first …

That primaquine and other drugs can trigger acute haemolytic anaemia in subjects who
have an inherited mutation of the glucose 6‐phosphate dehydrogenase (G6 PD) gene has …

G6PD was discovered and biochemically characterized in 1932 by Otto Warburg and Walter
Christian 1 in yeast and in red cells as an enzyme with a redox function. It was one of the first …

Since ancient times, humankind has had to struggle against the persistent onslaught of
pathogenic microorganisms. Nowadays, malaria is still the most important infectious disease …

Multidrug resistance has rendered monotherapy for malaria useless in most parts of the
world, and has also compromised the usefulness of many of the available combination …

Glucose-6-phosphate dehydrogenase (G6PD) deficiency is relatively common in
populations exposed to malaria. This deficiency appears to provide some protection from …

Oxidative agents can cause acute haemolytic anaemia in persons with G6PD deficiency.
Understanding the relationship between G6PD genotype and the phenotypic expression of …

In the past 21 years, a modest increase in the range of antimalarial drugs approved for
clinical use has been complemented by a more impressive expansion in the analysis and …

Malaria continues to be a potentially fatal threat to almost half of the world's population. In
light of this threat, the armory to fight this disease is rather limited. Resistance against the …

Malaria has been a human health concern ever since the dawn of mankind, but despite the
huge struggles made to date to fight this infection, in 2012 over half a million people were …