The discovery of cisplatin's antitumor activity in 1969 prompted the search for novel metal-
containing complexes as potential anticancer drugs. Among these novel complexes, metal N …

Conventional chemotherapy and radiation treatment are two cornerstones of cancer
treatment but efforts are required to improve their “therapeutic window”. The development of …

The aim of the present study was to investigate the ameliorative effect of curcumin (CMN)
against acute cadmium chloride (CdCl 2) toxicity on male reproductive system in rats. CdCl …

This study investigated the probable protective effect of resveratrol against cisplatin-induced
testicular and epididymal toxicity in rats. Body weights of the animals showed no significant …

Acrylamide (ACR) is a toxic chemical frequently encountered in daily life, posing health
risks. This study aimed to elucidate the molecular-level mechanism of ACR's toxic effects on …

The target of this study was to explore the role of mitochondria mediated apoptosis and
inflammation in cisplatin-induced testicular damage and to evaluate the ameliorative effect …

Cisplatin is an effective antineoplastic drug that is usually used to treat a number of different
types of cancer in the clinic. One of the most notable side effects of cisplatin use is infertility …

Purpose Testicular toxicity is one of the most important side effects of cisplatin (CP) therapy.
Alpha-pinene (AP) is a naturally occurring monoterpene with antioxidant character in plants …

Cisplatin (CIS) is widely applied for its antihematological malignancies properties and as
antisolid tumors drugs. However, it could cause testicular damage related with oxidative …

OBJECTIVE: Di-n-butyl phthalate (DBP) is a ubiquitous environmental pollutant, extensively
used as a plasticizer in many products, including plastics, cosmetics, and medical devices …