Cerebellum in Alzheimer's disease and other neurodegenerative diseases: an emerging research frontier
C Yang, G Liu, X Chen, W Le - MedComm, 2024 - Wiley Online Library
The cerebellum is crucial for both motor and nonmotor functions. Alzheimer's disease (AD),
alongside other dementias such as vascular dementia (VaD), Lewy body dementia (DLB) …
alongside other dementias such as vascular dementia (VaD), Lewy body dementia (DLB) …
Decoupling between brain activity and cerebrospinal fluid movement in neurological disorders
X Liu - Journal of Magnetic Resonance Imaging, 2024 - Wiley Online Library
Recent research has identified a link between the global mean signal of resting‐state
functional MRI (fMRI) and macro‐scale cerebrospinal fluid movement, indicating the …
functional MRI (fMRI) and macro‐scale cerebrospinal fluid movement, indicating the …
[HTML][HTML] Neurovascular coupling dysfunction of visual network organization in Parkinson's disease
Parkinson's disease (PD) has been showed perfusion and neural activity alterations in
specific regions, such as the motor and visual networks; however, the clinical significance of …
specific regions, such as the motor and visual networks; however, the clinical significance of …
Integrative omics analysis reveals epigenomic and transcriptomic signatures underlying brain structural deficits in major depressive disorder
Several lines of evidence support the involvement of transcriptomic and epigenetic
mechanisms in the brain structural deficits of major depressive disorder (MDD) separately …
mechanisms in the brain structural deficits of major depressive disorder (MDD) separately …
Altered large‐scale dynamic connectivity patterns in Alzheimer's disease and mild cognitive impairment patients: A machine learning study
Alzheimer's disease (AD) is a common neurodegeneration disease associated with
substantial disruptions in the brain network. However, most studies investigated static …
substantial disruptions in the brain network. However, most studies investigated static …
[HTML][HTML] Self-supervised multimodal learning for group inferences from MRI data: Discovering disorder-relevant brain regions and multimodal links
In recent years, deep learning approaches have gained significant attention in predicting
brain disorders using neuroimaging data. However, conventional methods often rely on …
brain disorders using neuroimaging data. However, conventional methods often rely on …
[HTML][HTML] Macaque Brainnetome Atlas: A multifaceted brain map with parcellation, connection, and histology
The rhesus macaque (Macaca mulatta) is a crucial experimental animal that shares many
genetic, brain organizational, and behavioral characteristics with humans. A macaque brain …
genetic, brain organizational, and behavioral characteristics with humans. A macaque brain …
[HTML][HTML] Local structural–functional coupling with counterfactual explanations for epilepsy prediction
The structural–functional brain connections coupling (SC–FC coupling) describes the
relationship between white matter structural connections (SC) and the corresponding …
relationship between white matter structural connections (SC) and the corresponding …
Potential therapeutic natural compounds for the treatment of Alzheimer's disease
Q Huang, W Wu, Y Wen, S Lu, C Zhao - Phytomedicine, 2024 - Elsevier
Background Alzheimer's disease (AD) is a complicated neurodegenerative disease with
cognitive impairment occurring in the older people, in which extracellular accumulation of β …
cognitive impairment occurring in the older people, in which extracellular accumulation of β …
β-Secretase-1: In Silico Drug Reposition for Alzheimer's Disease
RA Galeana-Ascencio, L Mendieta, DI Limon… - International Journal of …, 2023 - mdpi.com
The β-secretase-1 enzyme (BACE-1) performs a key role in the production of beta-Amyloid
protein (Aβ), which is associated with the development of Alzheimer's disease (AD). The …
protein (Aβ), which is associated with the development of Alzheimer's disease (AD). The …