Cytochrome P450s comprise a superfamily of heme-thiolate proteins named for the spectral
absorbance peak of their carbon-monoxide-bound species at 450 nm. Having been found in …

Kinetoplast DNA is the mitochondrial DNA of trypanosomatid protozoa that cause diseases
in humans, livestock and plants. They consist of a complex network of interlocked DNA …

The neutral theory often is presented as a theory of``noise''or silent changes at an
isolated``molecular level,''relevant to marking the steady pace of divergence, but not to the …

The Leishmania species cause a variety of human disease syndromes. Methods for
diagnosis and species differentiation are insensitive and many require invasive sampling …

Although the collection of completely sequenced mitochondrial genomes is expanding
rapidly, only recently has a phylogenetically broad representation of mtDNA sequences from …

Molecular data (particularly sequence analyses) have established that two eukaryotic
organelles, the mitochondrion and the plastid, are the descendants of endosymbiotic (eu) …

RNA helicases represent a large family of proteins that have been detected in almost all
biological systems where RNA plays a central role. They are ubiquitously distributed over a …

The term 'RNA editing'encompases a variety of processes that change the primary
nucleotide sequence of an RNA transcript from that of its encoding DNA. As in the case of …

Mitochondrial transcripts in kinetoplastids undergo remarkable posttranscriptional editing by
uridylate insertion and deletion. The often dramatic remodeling of pre-mRNA sequences is …

The metabolism of Trypanosoma brucei undergoes a significant change as the parasite
differentiates from the mammalian bloodstream form to the form found in the tse-tse fly …