Interethnic differences in pharmacokinetics of antibacterials

D Tsai, JA Jamal, JS Davis, J Lipman… - Clinical …, 2015 - Springer
Background Optimal antibacterial dosing is imperative for maximising clinical outcome.
Many factors can contribute to changes in the pharmacokinetics of antibacterials to the …

Efficacy and quality of antibacterial generic products approved for human use: a systematic review

P Tattevin, AC Crémieux, C Rabaud… - Clinical infectious …, 2014 - academic.oup.com
Background. Concerns have recently emerged about the efficacy and the quality of
antibacterial generic products approved for use in humans. Methods. We searched Medline …

Formulation development and optimization of taste-masked azithromycin oral suspension with ion exchange resins: Bioanalytical method development and validation …

F Siddiqui, MH Shoaib, FR Ahmed, F Qazi… - Journal of Drug Delivery …, 2023 - Elsevier
The study is based on preparing taste-masked oral suspension of azithromycin using ion
exchange resins Kyron T135 and Doshion-P542 AB. The complexation process was …

Azithromycin extraction from municipal wastewater and quantitation using liquid chromatography/mass spectrometry

DE Koch, A Bhandari, L Close, RP Hunter - Journal of Chromatography A, 2005 - Elsevier
Azithromycin is a broad spectrum antimicrobial agent that is approved in the United States
for use in humans. Due to azithromycin's low rate of metabolism it is likely to be found in …

Bioavailability and pharmacokinetic comparison between generic and branded azithromycin capsule: a randomized, double-blind, 2-way crossover in healthy male …

J Boonleang, K Panrat, C Tantana, S Krittathanmakul… - Clinical …, 2007 - Elsevier
BACKGROUND:: Azithromycin is a semisynthetic azalide antibiotic with extensive tissue
penetration and a prolonged t12. It is used once daily for 3 days in the treatment of a number …

A Reference‐Scaled Average Bioequivalence Study of Azithromycin Tablets Manufactured in China and the United States: An Open‐Label, Randomized, Single …

B Ge, C Li, H Wei, Y Ding, M Wu, Y Liu… - Clinical …, 2022 - Wiley Online Library
Azithromycin (Zithromax) is an azalide antibiotic that binds to the 50S ribosomal subunit of
the susceptible organism and thereby interferes with its protein synthesis. An open‐label …

Investigating the critical variables of azithromycin oral absorption using in vitro tests and PBPK modeling

M Guimarães, P Somville, M Vertzoni… - Journal of Pharmaceutical …, 2021 - Elsevier
Azithromycin is an antibiotic listed in the essential list of medicines for adults and pediatrics.
Conflicting evidence has been found regarding azithromycin classification according to the …

Pharmacokinetics and Bioequivalence of 2 Azithromycin Tablet Formulations: A Randomized, Open‐Label, 2‐Stage Crossover Study in Healthy Volunteers

CW Leong, KM Yee, J Nalaiya, Z Kassim… - Clinical …, 2022 - Wiley Online Library
The current study aimed to assess the bioequivalence of a new branded azithromycin with
the reference formulation. An open‐label, randomized, 2‐stage, crossover study design was …

Pharmacokinetics and Bioequivalence of Two Formulations of Azithromycin Tablets: A Randomized, Single-Dose, Three-Period, Crossover Study in Healthy Chinese …

Y Chen, L Ye, J Mei, M Tian, M Xu, Q **, X Yu, S Yang… - Drugs in R&D, 2024 - Springer
Abstract Background and Objective Azithromycin is the first azalide antibiotic that is related
to the macrolide family of antibiotics. Bioequivalence studies in China are initiated by the …

Determination of azithromycin in human plasma by LC-MS-MS and its pharmacokinetics

Z Xue-Min, L Jie, G Juan… - Die Pharmazie-An …, 2007 - ingentaconnect.com
A LC-MS-MS assay has been developed for determinating of azithromycin in human plasma
and investigating the pharmacokinetics in Chinese male volunteers following oral …