The proteins of the BCL-2 family are key regulators of mitochondrial apoptosis, acting as
either promoters or inhibitors of cell death. The functional interplay and balance between the …

PANoptosis, a new research hotspot at the moment, is a cell death pattern in which
pyroptosis, apoptosis, and necroptosis all occur in the same cell population. In essence …

Currently, there is no disease-modifying treatment available for Alzheimer's and Parkinson's
disease (AD and PD) and that includes the highly controversial approval of the Aβ-targeting …

Breast cancer is one of the leading causes of mortality among women worldwide due to
aggressive behavior, early metastasis, resistance to existing chemotherapeutic agent and …

Many modalities of cancer therapy induce mechanisms of treatment resistance and escape
pathways during chronic treatments, including photodynamic therapy (PDT). It is …

Bax and Bak are two nuclear-encoded proteins present in higher eukaryotes that are able to
pierce the mitochondrial outer membrane to mediate cell death by apoptosis. Thus …

Increasing evidence suggests that dietary carotenoids may reduce the risk of breast cancer.
However, anti-breast cancer effects of carotenoids have been controversial, albeit …

Plasma medicine is a rapidly expanding new field of interdisciplinary research that
combines physics, chemistry, biology, and medicine. Nonthermal atmospheric pressure …

Myocardial infarction (MI) is a leading cause of morbidity and mortality worldwide. As
mitochondrial dysfunction critically contributes to the pathogenesis of MI, intensive research …

Traumatic brain injury (TBI) is a major health and socioeconomic problem throughout the
world. It is a complicated pathological process that consists of primary insults and a …