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Post-transcriptional regulatory functions of mammalian pumilio proteins
Mammalian Pumilio proteins, PUM1 and PUM2, are members of the PUF family of sequence-
specific RNA-binding proteins. In this review, we explore their mechanisms, regulatory …
specific RNA-binding proteins. In this review, we explore their mechanisms, regulatory …
[HTML][HTML] Genetic conservation across SARS-CoV-2 non-structural proteins–Insights into possible targets for treatment of future viral outbreaks
The majority of SARS-CoV-2 therapeutic development work has focussed on targeting the
spike protein, viral polymerase and proteases. As the pandemic progressed, many studies …
spike protein, viral polymerase and proteases. As the pandemic progressed, many studies …
[کتاب][B] Alignment of biological sequences with Jalview
JB Procter, GM Carstairs, B Soares, K Mourão… - 2021 - Springer
In this chapter, we introduce core functionality of the Jalview interactive platform for the
creation, analysis, and publication of multiple sequence alignments. A workflow is described …
creation, analysis, and publication of multiple sequence alignments. A workflow is described …
Mechanism of membrane-tethered mitochondrial protein synthesis
Mitochondrial ribosomes (mitoribosomes) are tethered to the mitochondrial inner membrane
to facilitate the cotranslational membrane insertion of the synthesized proteins. We report …
to facilitate the cotranslational membrane insertion of the synthesized proteins. We report …
Structure of the ceramide-bound SPOTS complex
JH Schäfer, C Körner, BM Esch, S Limar… - Nature …, 2023 - nature.com
Sphingolipids are structural membrane components that also function in cellular stress
responses. The serine palmitoyltransferase (SPT) catalyzes the rate-limiting step in …
responses. The serine palmitoyltransferase (SPT) catalyzes the rate-limiting step in …
The structure of neurofibromin isoform 2 reveals different functional states
The autosomal dominant monogenetic disease neurofibromatosis type 1 (NF1) affects
approximately one in 3,000 individuals and is caused by mutations in the NF1 tumour …
approximately one in 3,000 individuals and is caused by mutations in the NF1 tumour …
Intracellular Ebola virus nucleocapsid assembly revealed by in situ cryo-electron tomography
Filoviruses, including the Ebola and Marburg viruses, cause hemorrhagic fevers with up to
90% lethality. The viral nucleocapsid is assembled by polymerization of the nucleoprotein …
90% lethality. The viral nucleocapsid is assembled by polymerization of the nucleoprotein …
Bactericidal effectors of the Stenotrophomonas maltophilia type IV secretion system: functional definition of the nuclease TfdA and structural determination of TfcB
Stenotrophomonas maltophilia expresses a type IV protein secretion system (T4SS) that
promotes contact-dependent killing of other bacteria and does so partly by secreting the …
promotes contact-dependent killing of other bacteria and does so partly by secreting the …
Genome-wide identification and analysis of the heat shock transcription factor family in moso bamboo (Phyllostachys edulis)
Heat shock transcription factors (HSFs) are central elements in the regulatory network that
controls plant heat stress response. They are involved in multiple transcriptional regulatory …
controls plant heat stress response. They are involved in multiple transcriptional regulatory …
[HTML][HTML] Genome-Wide Identification and Expression Analysis of LBD Transcription Factor Genes in Passion Fruit (Passiflora edulis)
J Liang, Z Hou, J Liao, Y Qin, L Wang, X Wang… - International Journal of …, 2022 - mdpi.com
The lateral organ boundary domain (LBD) gene is a plant-specific transcription factor that
plays a crucial role in plant growth and development, including the development of lateral …
plays a crucial role in plant growth and development, including the development of lateral …