In the era of precision medicine, it has been increasingly recognized that individuals with a
certain disease are complex and different from each other. Due to the underestimation of the …

The treatment for COVID-19 has evolved rapidly since the start of the pandemic and now
consists mainly of antiviral and immunomodulatory agents. Antivirals, such as remdesivir …

Obesity, diabetes mellitus (mostly type 2), and COVID-19 show mutual interactions because
they are not only risk factors for both acute and chronic COVID-19 manifestations, but also …

Dexamethasone is a life-saving treatment for severe COVID-19, yet its mechanism of action
is unknown, and many patients deteriorate or die despite timely treatment initiation. Here, we …

Description: In March 2020, the White House Coronavirus Task Force determined that
clinicians in the United States needed expert treatment guidelines to optimally manage …

The wide and rapid spread of the COVID-19 pandemic has placed an unanticipated burden
on the global healthcare sector. This necessitated a swift response from the international …

Importance Severe pulmonary infections, including COVID-19, community-acquired
pneumonia, influenza, andPneumocystispneumonia, are a leading cause of death among …

The COVID-19 pandemic is prompting extensive investigation into potential treatments,
including the use of corticosteroids to manage inflammation and mitigate severe disease …

Dexamethasone is the standard of care for critically ill patients with COVID-19, but the
mechanisms by which it decreases mortality and its immunological effects in this setting are …

Introduction The impact of different doses of dexamethasone on outcomes from acute
COVID-19 pneumonia is unknown. Methods We performed a systematic review and meta …